Daily Papers

The Segment Anything Model 2 (SAM 2) has emerged as a powerful foundation model for object segmentation in both images and videos, paving the way for various downstream video applications. The crucial design of SAM 2 for video segmentation is its memory module, which prompts object-aware memories from previous frames for current frame prediction. However, its greedy-selection memory design suffers from the "error accumulation" problem, where an errored or missed mask will cascade and influence the segmentation of the subsequent frames, which limits the performance of SAM 2 toward complex long-term videos. To this end, we introduce SAM2Long, an improved training-free video object segmentation strategy, which considers the segmentation uncertainty within each frame and chooses the video-level optimal results from multiple segmentation pathways in a constrained tree search manner. In practice, we maintain a fixed number of segmentation pathways throughout the video. For each frame, multiple masks are proposed based on the existing pathways, creating various candidate branches. We then select the same fixed number of branches with higher cumulative scores as the new pathways for the next frame. After processing the final frame, the pathway with the highest cumulative score is chosen as the final segmentation result. Benefiting from its heuristic search design, SAM2Long is robust toward occlusions and object reappearances, and can effectively segment and track objects for complex long-term videos. Notably, SAM2Long achieves an average improvement of 3.0 points across all 24 head-to-head comparisons, with gains of up to 5.3 points in J&F on long-term video object segmentation benchmarks such as SA-V and LVOS. The code is released at https://github.com/Mark12Ding/SAM2Long.

In this paper, we present UNet++, a new, more powerful architecture for medical image segmentation. Our architecture is essentially a deeply-supervised encoder-decoder network where the encoder and decoder sub-networks are connected through a series of nested, dense skip pathways. The re-designed skip pathways aim at reducing the semantic gap between the feature maps of the encoder and decoder sub-networks. We argue that the optimizer would deal with an easier learning task when the feature maps from the decoder and encoder networks are semantically similar. We have evaluated UNet++ in comparison with U-Net and wide U-Net architectures across multiple medical image segmentation tasks: nodule segmentation in the low-dose CT scans of chest, nuclei segmentation in the microscopy images, liver segmentation in abdominal CT scans, and polyp segmentation in colonoscopy videos. Our experiments demonstrate that UNet++ with deep supervision achieves an average IoU gain of 3.9 and 3.4 points over U-Net and wide U-Net, respectively.

Open-vocabulary 3D instance segmentation transcends traditional closed-vocabulary methods by enabling the identification of both previously seen and unseen objects in real-world scenarios. It leverages a dual-modality approach, utilizing both 3D point clouds and 2D multi-view images to generate class-agnostic object mask proposals. Previous efforts predominantly focused on enhancing 3D mask proposal models; consequently, the information that could come from 2D association to 3D was not fully exploited. This bias towards 3D data, while effective for familiar indoor objects, limits the system's adaptability to new and varied object types, where 2D models offer greater utility. Addressing this gap, we introduce Zero-Shot Dual-Path Integration Framework that equally values the contributions of both 3D and 2D modalities. Our framework comprises three components: 3D pathway, 2D pathway, and Dual-Path Integration. 3D pathway generates spatially accurate class-agnostic mask proposals of common indoor objects from 3D point cloud data using a pre-trained 3D model, while 2D pathway utilizes pre-trained open-vocabulary instance segmentation model to identify a diverse array of object proposals from multi-view RGB-D images. In Dual-Path Integration, our Conditional Integration process, which operates in two stages, filters and merges the proposals from both pathways adaptively. This process harmonizes output proposals to enhance segmentation capabilities. Our framework, utilizing pre-trained models in a zero-shot manner, is model-agnostic and demonstrates superior performance on both seen and unseen data, as evidenced by comprehensive evaluations on the ScanNet200 and qualitative results on ARKitScenes datasets.

We propose a minimal path method to simultaneously compute segmentation masks and extract centerlines of tubular structures with line-topology. Minimal path methods are commonly used for the segmentation of tubular structures in a wide variety of applications. Recent methods use features extracted by CNNs, and often outperform methods using hand-tuned features. However, for CNN-based methods, the samples used for training may be generated inappropriately, so that they can be very different from samples encountered during inference. We approach this discrepancy by introducing a novel iterative training scheme, which enables generating better training samples specifically tailored for the minimal path methods without changing existing annotations. In our method, segmentation masks and centerlines are not determined after one another by post-processing, but obtained using the same steps. Our method requires only very few annotated training images. Comparison with seven previous approaches on three public datasets, including satellite images and medical images, shows that our method achieves state-of-the-art results both for segmentation masks and centerlines.

For many segmentation tasks, especially for the biomedical image, the topological prior is vital information which is useful to exploit. The containment/nesting is a typical inter-class geometric relationship. In the MICCAI Brain tumor segmentation challenge, with its three hierarchically nested classes 'whole tumor', 'tumor core', 'active tumor', the nested classes relationship is introduced into the 3D-residual-Unet architecture. The network comprises a context aggregation pathway and a localization pathway, which encodes increasingly abstract representation of the input as going deeper into the network, and then recombines these representations with shallower features to precisely localize the interest domain via a localization path. The nested-class-prior is combined by proposing the multi-class activation function and its corresponding loss function. The model is trained on the training dataset of Brats2018, and 20% of the dataset is regarded as the validation dataset to determine parameters. When the parameters are fixed, we retrain the model on the whole training dataset. The performance achieved on the validation leaderboard is 86%, 77% and 72% Dice scores for the whole tumor, enhancing tumor and tumor core classes without relying on ensembles or complicated post-processing steps. Based on the same start-of-the-art network architecture, the accuracy of nested-class (enhancing tumor) is reasonably improved from 69% to 72% compared with the traditional Softmax-based method which blind to topological prior.

Vision Transformer models exhibit immense power yet remain opaque to human understanding, posing challenges and risks for practical applications. While prior research has attempted to demystify these models through input attribution and neuron role analysis, there's been a notable gap in considering layer-level information and the holistic path of information flow across layers. In this paper, we investigate the significance of influential neuron paths within vision Transformers, which is a path of neurons from the model input to output that impacts the model inference most significantly. We first propose a joint influence measure to assess the contribution of a set of neurons to the model outcome. And we further provide a layer-progressive neuron locating approach that efficiently selects the most influential neuron at each layer trying to discover the crucial neuron path from input to output within the target model. Our experiments demonstrate the superiority of our method finding the most influential neuron path along which the information flows, over the existing baseline solutions. Additionally, the neuron paths have illustrated that vision Transformers exhibit some specific inner working mechanism for processing the visual information within the same image category. We further analyze the key effects of these neurons on the image classification task, showcasing that the found neuron paths have already preserved the model capability on downstream tasks, which may also shed some lights on real-world applications like model pruning. The project website including implementation code is available at https://foundation-model-research.github.io/NeuronPath/.

Unsupervised learning from visual data is one of the most difficult challenges in computer vision, being a fundamental task for understanding how visual recognition works. From a practical point of view, learning from unsupervised visual input has an immense practical value, as very large quantities of unlabeled videos can be collected at low cost. In this paper, we address the task of unsupervised learning to detect and segment foreground objects in single images. We achieve our goal by training a student pathway, consisting of a deep neural network. It learns to predict from a single input image (a video frame) the output for that particular frame, of a teacher pathway that performs unsupervised object discovery in video. Our approach is different from the published literature that performs unsupervised discovery in videos or in collections of images at test time. We move the unsupervised discovery phase during the training stage, while at test time we apply the standard feed-forward processing along the student pathway. This has a dual benefit: firstly, it allows in principle unlimited possibilities of learning and generalization during training, while remaining very fast at testing. Secondly, the student not only becomes able to detect in single images significantly better than its unsupervised video discovery teacher, but it also achieves state of the art results on two important current benchmarks, YouTube Objects and Object Discovery datasets. Moreover, at test time, our system is at least two orders of magnitude faster than other previous methods.

We present an end-to-end deep learning segmentation method by combining a 3D UNet architecture with a graph neural network (GNN) model. In this approach, the convolutional layers at the deepest level of the UNet are replaced by a GNN-based module with a series of graph convolutions. The dense feature maps at this level are transformed into a graph input to the GNN module. The incorporation of graph convolutions in the UNet provides nodes in the graph with information that is based on node connectivity, in addition to the local features learnt through the downsampled paths. This information can help improve segmentation decisions. By stacking several graph convolution layers, the nodes can access higher order neighbourhood information without substantial increase in computational expense. We propose two types of node connectivity in the graph adjacency: i) one predefined and based on a regular node neighbourhood, and ii) one dynamically computed during training and using the nearest neighbour nodes in the feature space. We have applied this method to the task of segmenting the airway tree from chest CT scans. Experiments have been performed on 32 CTs from the Danish Lung Cancer Screening Trial dataset. We evaluate the performance of the UNet-GNN models with two types of graph adjacency and compare it with the baseline UNet.

Semantic segmentation requires both rich spatial information and sizeable receptive field. However, modern approaches usually compromise spatial resolution to achieve real-time inference speed, which leads to poor performance. In this paper, we address this dilemma with a novel Bilateral Segmentation Network (BiSeNet). We first design a Spatial Path with a small stride to preserve the spatial information and generate high-resolution features. Meanwhile, a Context Path with a fast downsampling strategy is employed to obtain sufficient receptive field. On top of the two paths, we introduce a new Feature Fusion Module to combine features efficiently. The proposed architecture makes a right balance between the speed and segmentation performance on Cityscapes, CamVid, and COCO-Stuff datasets. Specifically, for a 2048x1024 input, we achieve 68.4% Mean IOU on the Cityscapes test dataset with speed of 105 FPS on one NVIDIA Titan XP card, which is significantly faster than the existing methods with comparable performance.

Unsupervised semantic segmentation aims to achieve high-quality semantic grouping without human-labeled annotations. With the advent of self-supervised pre-training, various frameworks utilize the pre-trained features to train prediction heads for unsupervised dense prediction. However, a significant challenge in this unsupervised setup is determining the appropriate level of clustering required for segmenting concepts. To address it, we propose a novel framework, CAusal Unsupervised Semantic sEgmentation (CAUSE), which leverages insights from causal inference. Specifically, we bridge intervention-oriented approach (i.e., frontdoor adjustment) to define suitable two-step tasks for unsupervised prediction. The first step involves constructing a concept clusterbook as a mediator, which represents possible concept prototypes at different levels of granularity in a discretized form. Then, the mediator establishes an explicit link to the subsequent concept-wise self-supervised learning for pixel-level grouping. Through extensive experiments and analyses on various datasets, we corroborate the effectiveness of CAUSE and achieve state-of-the-art performance in unsupervised semantic segmentation.

The interactive segmentation task consists in the creation of object segmentation masks based on user interactions. The most common way to guide a model towards producing a correct segmentation consists in clicks on the object and background. The recently published Segment Anything Model (SAM) supports a generalized version of the interactive segmentation problem and has been trained on an object segmentation dataset which contains 1.1B masks. Though being trained extensively and with the explicit purpose of serving as a foundation model, we show significant limitations of SAM when being applied for interactive segmentation on novel domains or object types. On the used datasets, SAM displays a failure rate FR_{30}@90 of up to 72.6 %. Since we still want such foundation models to be immediately applicable, we present a framework that can adapt SAM during immediate usage. For this we will leverage the user interactions and masks, which are constructed during the interactive segmentation process. We use this information to generate pseudo-labels, which we use to compute a loss function and optimize a part of the SAM model. The presented method causes a relative reduction of up to 48.1 % in the FR_{20}@85 and 46.6 % in the FR_{30}@90 metrics.

Interactive image segmentation enables annotators to efficiently perform pixel-level annotation for segmentation tasks. However, the existing interactive segmentation pipeline suffers from inefficient computations of interactive models because of the following two issues. First, annotators' later click is based on models' feedback of annotators' former click. This serial interaction is unable to utilize model's parallelism capabilities. Second, in each interaction step, the model handles the invariant image along with the sparse variable clicks, resulting in a process that's highly repetitive and redundant. For efficient computations, we propose a method named InterFormer that follows a new pipeline to address these issues. InterFormer extracts and preprocesses the computationally time-consuming part i.e. image processing from the existing process. Specifically, InterFormer employs a large vision transformer (ViT) on high-performance devices to preprocess images in parallel, and then uses a lightweight module called interactive multi-head self attention (I-MSA) for interactive segmentation. Furthermore, the I-MSA module's deployment on low-power devices extends the practical application of interactive segmentation. The I-MSA module utilizes the preprocessed features to efficiently response to the annotator inputs in real-time. The experiments on several datasets demonstrate the effectiveness of InterFormer, which outperforms previous interactive segmentation models in terms of computational efficiency and segmentation quality, achieve real-time high-quality interactive segmentation on CPU-only devices. The code is available at https://github.com/YouHuang67/InterFormer.

We propose a bidirectional consecutively connected two-pathway network (BCCN) for efficient gesture recognition. The BCCN consists of two pathways: (i) a keyframe pathway and (ii) a temporal-attention pathway. The keyframe pathway is configured using the skeleton-based keyframe selection module. Keyframes pass through the pathway to extract the spatial feature of itself, and the temporal-attention pathway extracts temporal semantics. Our model improved gesture recognition performance in videos and obtained better activation maps for spatial and temporal properties. Tests were performed on the Chalearn dataset, the ETRI-Activity 3D dataset, and the Toyota Smart Home dataset.

In-context segmentation aims at segmenting novel images using a few labeled example images, termed as "in-context examples", exploring content similarities between examples and the target. The resulting models can be generalized seamlessly to novel segmentation tasks, significantly reducing the labeling and training costs compared with conventional pipelines. However, in-context segmentation is more challenging than classic ones due to its meta-learning nature, requiring the model to learn segmentation rules conditioned on a few samples, not just the segmentation. Unlike previous work with ad-hoc or non-end-to-end designs, we propose SEGIC, an end-to-end segment-in-context framework built upon a single vision foundation model (VFM). In particular, SEGIC leverages the emergent correspondence within VFM to capture dense relationships between target images and in-context samples. As such, information from in-context samples is then extracted into three types of instructions, i.e. geometric, visual, and meta instructions, serving as explicit conditions for the final mask prediction. SEGIC is a straightforward yet effective approach that yields state-of-the-art performance on one-shot segmentation benchmarks. Notably, SEGIC can be easily generalized to diverse tasks, including video object segmentation and open-vocabulary segmentation. Code will be available at https://github.com/MengLcool/SEGIC.

The widespread use of vector graphics creates a significant demand for vectorization methods. While recent learning-based techniques have shown their capability to create vector images of clear topology, filling these primitives with gradients remains a challenge. In this paper, we propose a segmentation-guided vectorization framework to convert raster images into concise vector graphics with radial gradient fills. With the guidance of an embedded gradient-aware segmentation subroutine, our approach progressively appends gradient-filled B\'ezier paths to the output, where primitive parameters are initiated with our newly designed initialization technique and are optimized to minimize our novel loss function. We build our method on a differentiable renderer with traditional segmentation algorithms to develop it as a model-free tool for raster-to-vector conversion. It is tested on various inputs to demonstrate its feasibility, independent of datasets, to synthesize vector graphics with improved visual quality and layer-wise topology compared to prior work.

Cell instance segmentation in cytology images has significant importance for biology analysis and cancer screening, while remains challenging due to 1) the extensive overlapping translucent cell clusters that cause the ambiguous boundaries, and 2) the confusion of mimics and debris as nuclei. In this work, we proposed a De-overlapping Network (DoNet) in a decompose-and-recombined strategy. A Dual-path Region Segmentation Module (DRM) explicitly decomposes the cell clusters into intersection and complement regions, followed by a Semantic Consistency-guided Recombination Module (CRM) for integration. To further introduce the containment relationship of the nucleus in the cytoplasm, we design a Mask-guided Region Proposal Strategy (MRP) that integrates the cell attention maps for inner-cell instance prediction. We validate the proposed approach on ISBI2014 and CPS datasets. Experiments show that our proposed DoNet significantly outperforms other state-of-the-art (SOTA) cell instance segmentation methods. The code is available at https://github.com/DeepDoNet/DoNet.

Promptable segmentation typically requires instance-specific manual prompts to guide the segmentation of each desired object. To minimize such a need, task-generic promptable segmentation has been introduced, which employs a single task-generic prompt to segment various images of different objects in the same task. Current methods use Multimodal Large Language Models (MLLMs) to reason detailed instance-specific prompts from a task-generic prompt for improving segmentation accuracy. The effectiveness of this segmentation heavily depends on the precision of these derived prompts. However, MLLMs often suffer hallucinations during reasoning, resulting in inaccurate prompting. While existing methods focus on eliminating hallucinations to improve a model, we argue that MLLM hallucinations can reveal valuable contextual insights when leveraged correctly, as they represent pre-trained large-scale knowledge beyond individual images. In this paper, we utilize hallucinations to mine task-related information from images and verify its accuracy for enhancing precision of the generated prompts. Specifically, we introduce an iterative Prompt-Mask Cycle generation framework (ProMaC) with a prompt generator and a mask generator.The prompt generator uses a multi-scale chain of thought prompting, initially exploring hallucinations for extracting extended contextual knowledge on a test image.These hallucinations are then reduced to formulate precise instance-specific prompts, directing the mask generator to produce masks that are consistent with task semantics by mask semantic alignment. The generated masks iteratively induce the prompt generator to focus more on task-relevant image areas and reduce irrelevant hallucinations, resulting jointly in better prompts and masks. Experiments on 5 benchmarks demonstrate the effectiveness of ProMaC. Code given in https://lwpyh.github.io/ProMaC/.

Existing visual perception systems focus on region-level segmentation in single-turn dialogues, relying on complex and explicit query instructions. Such systems cannot reason at the pixel level and comprehend dynamic user intent that changes over interaction. Our work tackles this issue by introducing a novel task, Pixel-level Reasoning Segmentation (Pixel-level RS) based on multi-turn conversations, tracking evolving user intent via multi-turn interactions for fine-grained segmentation. To establish a benchmark for this novel task, we build a Pixel-level ReasonIng Segmentation Dataset Based on Multi-Turn Conversations (PRIST), comprising 24k utterances from 8.3k multi-turn conversational scenarios with segmentation targets. Building on PRIST, we further propose MIRAS, a Multi-turn Interactive ReAsoning Segmentation framework, integrates pixel-level segmentation with robust multi-turn conversation understanding, generating pixel-grounded explanations aligned with user intent. The PRIST dataset and MIRSA framework fill the gap in pixel-level reasoning segmentation. Experimental results on the PRIST dataset demonstrate that our method outperforms current segmentation-specific baselines in terms of segmentation and LLM-based reasoning metrics. The code and data are available at: https://github.com/ccccai239/PixelRIST.

Segmenting an object in a video presents significant challenges. Each pixel must be accurately labelled, and these labels must remain consistent across frames. The difficulty increases when the segmentation is with arbitrary granularity, meaning the number of segments can vary arbitrarily, and masks are defined based on only one or a few sample images. In this paper, we address this issue by employing a pre-trained text to image diffusion model supplemented with an additional tracking mechanism. We demonstrate that our approach can effectively manage various segmentation scenarios and outperforms state-of-the-art alternatives.

Heatwaves pose significant health risks, particularly due to prolonged exposure to high summer temperatures. Vulnerable groups, especially pedestrians and cyclists on sun-exposed sidewalks, motivate the development of a route planning method that incorporates somatosensory temperature effects through shade ratio consideration. This paper is the first to introduce a pipeline that utilizes segmentation foundation models to extract shaded areas from high-resolution satellite images. These areas are then integrated into a multi-layered road map, enabling users to customize routes based on a balance between distance and shade exposure, thereby enhancing comfort and health during outdoor activities. Specifically, we construct a graph-based representation of the road map, where links indicate connectivity and are updated with shade ratio data for dynamic route planning. This system is already implemented online, with a video demonstration, and will be specifically adapted to assist travelers during the 2024 Olympic Games in Paris.

We present MeshSegmenter, a simple yet effective framework designed for zero-shot 3D semantic segmentation. This model successfully extends the powerful capabilities of 2D segmentation models to 3D meshes, delivering accurate 3D segmentation across diverse meshes and segment descriptions. Specifically, our model leverages the Segment Anything Model (SAM) model to segment the target regions from images rendered from the 3D shape. In light of the importance of the texture for segmentation, we also leverage the pretrained stable diffusion model to generate images with textures from 3D shape, and leverage SAM to segment the target regions from images with textures. Textures supplement the shape for segmentation and facilitate accurate 3D segmentation even in geometrically non-prominent areas, such as segmenting a car door within a car mesh. To achieve the 3D segments, we render 2D images from different views and conduct segmentation for both textured and untextured images. Lastly, we develop a multi-view revoting scheme that integrates 2D segmentation results and confidence scores from various views onto the 3D mesh, ensuring the 3D consistency of segmentation results and eliminating inaccuracies from specific perspectives. Through these innovations, MeshSegmenter offers stable and reliable 3D segmentation results both quantitatively and qualitatively, highlighting its potential as a transformative tool in the field of 3D zero-shot segmentation. The code is available at https://github.com/zimingzhong/MeshSegmenter.

Current 3D scene segmentation methods are heavily dependent on manually annotated 3D training datasets. Such manual annotations are labor-intensive, and often lack fine-grained details. Importantly, models trained on this data typically struggle to recognize object classes beyond the annotated classes, i.e., they do not generalize well to unseen domains and require additional domain-specific annotations. In contrast, 2D foundation models demonstrate strong generalization and impressive zero-shot abilities, inspiring us to incorporate these characteristics from 2D models into 3D models. Therefore, we explore the use of image segmentation foundation models to automatically generate training labels for 3D segmentation. We propose Segment3D, a method for class-agnostic 3D scene segmentation that produces high-quality 3D segmentation masks. It improves over existing 3D segmentation models (especially on fine-grained masks), and enables easily adding new training data to further boost the segmentation performance -- all without the need for manual training labels.

Salient segmentation aims to segment out attention-grabbing regions, a critical yet challenging task and the foundation of many high-level computer vision applications. It requires semantic-aware grouping of pixels into salient regions and benefits from the utilization of global multi-scale contexts to achieve good local reasoning. Previous works often address it as two-class segmentation problems utilizing complicated multi-step procedures including refinement networks and complex graphical models. We argue that semantic salient segmentation can instead be effectively resolved by reformulating it as a simple yet intuitive pixel-pair based connectivity prediction task. Following the intuition that salient objects can be naturally grouped via semantic-aware connectivity between neighboring pixels, we propose a pure Connectivity Net (ConnNet). ConnNet predicts connectivity probabilities of each pixel with its neighboring pixels by leveraging multi-level cascade contexts embedded in the image and long-range pixel relations. We investigate our approach on two tasks, namely salient object segmentation and salient instance-level segmentation, and illustrate that consistent improvements can be obtained by modeling these tasks as connectivity instead of binary segmentation tasks for a variety of network architectures. We achieve state-of-the-art performance, outperforming or being comparable to existing approaches while reducing inference time due to our less complex approach.

The way that information propagates in neural networks is of great importance. In this paper, we propose Path Aggregation Network (PANet) aiming at boosting information flow in proposal-based instance segmentation framework. Specifically, we enhance the entire feature hierarchy with accurate localization signals in lower layers by bottom-up path augmentation, which shortens the information path between lower layers and topmost feature. We present adaptive feature pooling, which links feature grid and all feature levels to make useful information in each feature level propagate directly to following proposal subnetworks. A complementary branch capturing different views for each proposal is created to further improve mask prediction. These improvements are simple to implement, with subtle extra computational overhead. Our PANet reaches the 1st place in the COCO 2017 Challenge Instance Segmentation task and the 2nd place in Object Detection task without large-batch training. It is also state-of-the-art on MVD and Cityscapes. Code is available at https://github.com/ShuLiu1993/PANet

Large-scale text-to-image diffusion models have significantly improved the state of the art in generative image modelling and allow for an intuitive and powerful user interface to drive the image generation process. Expressing spatial constraints, e.g. to position specific objects in particular locations, is cumbersome using text; and current text-based image generation models are not able to accurately follow such instructions. In this paper we consider image generation from text associated with segments on the image canvas, which combines an intuitive natural language interface with precise spatial control over the generated content. We propose ZestGuide, a zero-shot segmentation guidance approach that can be plugged into pre-trained text-to-image diffusion models, and does not require any additional training. It leverages implicit segmentation maps that can be extracted from cross-attention layers, and uses them to align the generation with input masks. Our experimental results combine high image quality with accurate alignment of generated content with input segmentations, and improve over prior work both quantitatively and qualitatively, including methods that require training on images with corresponding segmentations. Compared to Paint with Words, the previous state-of-the art in image generation with zero-shot segmentation conditioning, we improve by 5 to 10 mIoU points on the COCO dataset with similar FID scores.

Image segmentation is usually addressed by training a model for a fixed set of object classes. Incorporating additional classes or more complex queries later is expensive as it requires re-training the model on a dataset that encompasses these expressions. Here we propose a system that can generate image segmentations based on arbitrary prompts at test time. A prompt can be either a text or an image. This approach enables us to create a unified model (trained once) for three common segmentation tasks, which come with distinct challenges: referring expression segmentation, zero-shot segmentation and one-shot segmentation. We build upon the CLIP model as a backbone which we extend with a transformer-based decoder that enables dense prediction. After training on an extended version of the PhraseCut dataset, our system generates a binary segmentation map for an image based on a free-text prompt or on an additional image expressing the query. We analyze different variants of the latter image-based prompts in detail. This novel hybrid input allows for dynamic adaptation not only to the three segmentation tasks mentioned above, but to any binary segmentation task where a text or image query can be formulated. Finally, we find our system to adapt well to generalized queries involving affordances or properties. Code is available at https://eckerlab.org/code/clipseg.

Semantic segmentation has made significant progress in recent years thanks to deep neural networks, but the common objective of generating a single segmentation output that accurately matches the image's content may not be suitable for safety-critical domains such as medical diagnostics and autonomous driving. Instead, multiple possible correct segmentation maps may be required to reflect the true distribution of annotation maps. In this context, stochastic semantic segmentation methods must learn to predict conditional distributions of labels given the image, but this is challenging due to the typically multimodal distributions, high-dimensional output spaces, and limited annotation data. To address these challenges, we propose a conditional categorical diffusion model (CCDM) for semantic segmentation based on Denoising Diffusion Probabilistic Models. Our model is conditioned to the input image, enabling it to generate multiple segmentation label maps that account for the aleatoric uncertainty arising from divergent ground truth annotations. Our experimental results show that CCDM achieves state-of-the-art performance on LIDC, a stochastic semantic segmentation dataset, and outperforms established baselines on the classical segmentation dataset Cityscapes.

Pancreatic cancer is one of the leading causes of cancer-related death. Accurate detection, segmentation, and differential diagnosis of the full taxonomy of pancreatic lesions, i.e., normal, seven major types of lesions, and other lesions, is critical to aid the clinical decision-making of patient management and treatment. However, existing works focus on segmentation and classification for very specific lesion types (PDAC) or groups. Moreover, none of the previous work considers using lesion prevalence-related non-imaging patient information to assist the differential diagnosis. To this end, we develop a meta-information-aware dual-path transformer and exploit the feasibility of classification and segmentation of the full taxonomy of pancreatic lesions. Specifically, the proposed method consists of a CNN-based segmentation path (S-path) and a transformer-based classification path (C-path). The S-path focuses on initial feature extraction by semantic segmentation using a UNet-based network. The C-path utilizes both the extracted features and meta-information for patient-level classification based on stacks of dual-path transformer blocks that enhance the modeling of global contextual information. A large-scale multi-phase CT dataset of 3,096 patients with pathology-confirmed pancreatic lesion class labels, voxel-wise manual annotations of lesions from radiologists, and patient meta-information, was collected for training and evaluations. Our results show that our method can enable accurate classification and segmentation of the full taxonomy of pancreatic lesions, approaching the accuracy of the radiologist's report and significantly outperforming previous baselines. Results also show that adding the common meta-information, i.e., gender and age, can boost the model's performance, thus demonstrating the importance of meta-information for aiding pancreatic disease diagnosis.

Recent advancements in image segmentation have focused on enhancing the efficiency of the models to meet the demands of real-time applications, especially on edge devices. However, existing research has primarily concentrated on single-task settings, especially on semantic segmentation, leading to redundant efforts and specialized architectures for different tasks. To address this limitation, we propose a novel architecture for efficient multi-task image segmentation, capable of handling various segmentation tasks without sacrificing efficiency or accuracy. We introduce BiSeNetFormer, that leverages the efficiency of two-stream semantic segmentation architectures and it extends them into a mask classification framework. Our approach maintains the efficient spatial and context paths to capture detailed and semantic information, respectively, while leveraging an efficient transformed-based segmentation head that computes the binary masks and class probabilities. By seamlessly supporting multiple tasks, namely semantic and panoptic segmentation, BiSeNetFormer offers a versatile solution for multi-task segmentation. We evaluate our approach on popular datasets, Cityscapes and ADE20K, demonstrating impressive inference speeds while maintaining competitive accuracy compared to state-of-the-art architectures. Our results indicate that BiSeNetFormer represents a significant advancement towards fast, efficient, and multi-task segmentation networks, bridging the gap between model efficiency and task adaptability.

While MLLMs have demonstrated adequate image understanding capabilities, they still struggle with pixel-level comprehension, limiting their practical applications. Current evaluation tasks like VQA and visual grounding remain too coarse to assess fine-grained pixel comprehension accurately. Though segmentation is foundational for pixel-level understanding, existing methods often require MLLMs to generate implicit tokens, decoded through external pixel decoders. This approach disrupts the MLLM's text output space, potentially compromising language capabilities and reducing flexibility and extensibility, while failing to reflect the model's intrinsic pixel-level understanding. Thus, we introduce the Human-Like Mask Annotation Task (HLMAT), a new paradigm where MLLMs mimic human annotators using interactive segmentation tools. Modeling segmentation as a multi-step Markov Decision Process, HLMAT enables MLLMs to iteratively generate text-based click points, achieving high-quality masks without architectural changes or implicit tokens. Through this setup, we develop SegAgent, a model fine-tuned on human-like annotation trajectories, which achieves performance comparable to state-of-the-art (SOTA) methods and supports additional tasks like mask refinement and annotation filtering. HLMAT provides a protocol for assessing fine-grained pixel understanding in MLLMs and introduces a vision-centric, multi-step decision-making task that facilitates exploration of MLLMs' visual reasoning abilities. Our adaptations of policy improvement method StaR and PRM-guided tree search further enhance model robustness in complex segmentation tasks, laying a foundation for future advancements in fine-grained visual perception and multi-step decision-making for MLLMs.

Melanoma is caused by the abnormal growth of melanocytes in human skin. Like other cancers, this life-threatening skin cancer can be treated with early diagnosis. To support a diagnosis by automatic skin lesion segmentation, several Fully Convolutional Network (FCN) approaches, specifically the U-Net architecture, have been proposed. The U-Net model with a symmetrical architecture has exhibited superior performance in the segmentation task. However, the locality restriction of the convolutional operation incorporated in the U-Net architecture limits its performance in capturing long-range dependency, which is crucial for the segmentation task in medical images. To address this limitation, recently a Transformer based U-Net architecture that replaces the CNN blocks with the Swin Transformer module has been proposed to capture both local and global representation. In this paper, we propose Att-SwinU-Net, an attention-based Swin U-Net extension, for medical image segmentation. In our design, we seek to enhance the feature re-usability of the network by carefully designing the skip connection path. We argue that the classical concatenation operation utilized in the skip connection path can be further improved by incorporating an attention mechanism. By performing a comprehensive ablation study on several skin lesion segmentation datasets, we demonstrate the effectiveness of our proposed attention mechanism.

Significant strides have been made using large vision-language models, like Stable Diffusion (SD), for a variety of downstream tasks, including image editing, image correspondence, and 3D shape generation. Inspired by these advancements, we explore leveraging these extensive vision-language models for segmenting images at any desired granularity using as few as one annotated sample by proposing SLiMe. SLiMe frames this problem as an optimization task. Specifically, given a single training image and its segmentation mask, we first extract attention maps, including our novel "weighted accumulated self-attention map" from the SD prior. Then, using the extracted attention maps, the text embeddings of Stable Diffusion are optimized such that, each of them, learn about a single segmented region from the training image. These learned embeddings then highlight the segmented region in the attention maps, which in turn can then be used to derive the segmentation map. This enables SLiMe to segment any real-world image during inference with the granularity of the segmented region in the training image, using just one example. Moreover, leveraging additional training data when available, i.e. few-shot, improves the performance of SLiMe. We carried out a knowledge-rich set of experiments examining various design factors and showed that SLiMe outperforms other existing one-shot and few-shot segmentation methods.

Document Layout Analysis, which is the task of identifying different semantic regions inside of a document page, is a subject of great interest for both computer scientists and humanities scholars as it represents a fundamental step towards further analysis tasks for the former and a powerful tool to improve and facilitate the study of the documents for the latter. However, many of the works currently present in the literature, especially when it comes to the available datasets, fail to meet the needs of both worlds and, in particular, tend to lean towards the needs and common practices of the computer science side, leading to resources that are not representative of the humanities real needs. For this reason, the present paper introduces U-DIADS-Bib, a novel, pixel-precise, non-overlapping and noiseless document layout analysis dataset developed in close collaboration between specialists in the fields of computer vision and humanities. Furthermore, we propose a novel, computer-aided, segmentation pipeline in order to alleviate the burden represented by the time-consuming process of manual annotation, necessary for the generation of the ground truth segmentation maps. Finally, we present a standardized few-shot version of the dataset (U-DIADS-BibFS), with the aim of encouraging the development of models and solutions able to address this task with as few samples as possible, which would allow for more effective use in a real-world scenario, where collecting a large number of segmentations is not always feasible.

Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models or adapting them to a new condition is costly due to the need for (manually) labeled data. The emergence of vision foundation models, especially Segment Anything, offers a path to universal segmentation for medical images, overcoming these issues. Here, we study how to improve Segment Anything for medical images by comparing different finetuning strategies on a large and diverse dataset. We evaluate the finetuned models on a wide range of interactive and (automatic) semantic segmentation tasks. We find that the performance can be clearly improved for interactive segmentation. However, semantic segmentation does not benefit from pretraining on medical images. Our best model, MedicoSAM, is publicly available at https://github.com/computational-cell-analytics/medico-sam. We show that it is compatible with existing tools for data annotation and believe that it will be of great practical value.

Image segmentation is a vital task for providing human assistance and enhancing autonomy in our daily lives. In particular, RGB-D segmentation-leveraging both visual and depth cues-has attracted increasing attention as it promises richer scene understanding than RGB-only methods. However, most existing efforts have primarily focused on semantic segmentation and thus leave a critical gap. There is a relative scarcity of instance-level RGB-D segmentation datasets, which restricts current methods to broad category distinctions rather than fully capturing the fine-grained details required for recognizing individual objects. To bridge this gap, we introduce three RGB-D instance segmentation benchmarks, distinguished at the instance level. These datasets are versatile, supporting a wide range of applications from indoor navigation to robotic manipulation. In addition, we present an extensive evaluation of various baseline models on these benchmarks. This comprehensive analysis identifies both their strengths and shortcomings, guiding future work toward more robust, generalizable solutions. Finally, we propose a simple yet effective method for RGB-D data integration. Extensive evaluations affirm the effectiveness of our approach, offering a robust framework for advancing toward more nuanced scene understanding.

Image segmentation plays an essential role in medicine for both diagnostic and interventional tasks. Segmentation approaches are either manual, semi-automated or fully-automated. Manual segmentation offers full control over the quality of the results, but is tedious, time consuming and prone to operator bias. Fully automated methods require no human effort, but often deliver sub-optimal results without providing users with the means to make corrections. Semi-automated approaches keep users in control of the results by providing means for interaction, but the main challenge is to offer a good trade-off between precision and required interaction. In this paper we present a deep learning (DL) based semi-automated segmentation approach that aims to be a "smart" interactive tool for region of interest delineation in medical images. We demonstrate its use for segmenting multiple organs on computed tomography (CT) of the abdomen. Our approach solves some of the most pressing clinical challenges: (i) it requires only one to a few user clicks to deliver excellent 2D segmentations in a fast and reliable fashion; (ii) it can generalize to previously unseen structures and "corner cases"; (iii) it delivers results that can be corrected quickly in a smart and intuitive way up to an arbitrary degree of precision chosen by the user and (iv) ensures high accuracy. We present our approach and compare it to other techniques and previous work to show the advantages brought by our method.

Although perception systems have made remarkable advancements in recent years, they still rely on explicit human instruction to identify the target objects or categories before executing visual recognition tasks. Such systems lack the ability to actively reason and comprehend implicit user intentions. In this work, we propose a new segmentation task -- reasoning segmentation. The task is designed to output a segmentation mask given a complex and implicit query text. Furthermore, we establish a benchmark comprising over one thousand image-instruction pairs, incorporating intricate reasoning and world knowledge for evaluation purposes. Finally, we present LISA: large Language Instructed Segmentation Assistant, which inherits the language generation capabilities of the multi-modal Large Language Model (LLM) while also possessing the ability to produce segmentation masks. We expand the original vocabulary with a <SEG> token and propose the embedding-as-mask paradigm to unlock the segmentation capability. Remarkably, LISA can handle cases involving: 1) complex reasoning; 2) world knowledge; 3) explanatory answers; 4) multi-turn conversation. Also, it demonstrates robust zero-shot capability when trained exclusively on reasoning-free datasets. In addition, fine-tuning the model with merely 239 reasoning segmentation image-instruction pairs results in further performance enhancement. Experiments show our method not only unlocks new reasoning segmentation capabilities but also proves effective in both complex reasoning segmentation and standard referring segmentation tasks. Code, models, and demo are at https://github.com/dvlab-research/LISA.

A single unexpected object on the road can cause an accident or may lead to injuries. To prevent this, we need a reliable mechanism for finding anomalous objects on the road. This task, called anomaly segmentation, can be a stepping stone to safe and reliable autonomous driving. Current approaches tackle anomaly segmentation by assigning an anomaly score to each pixel and by grouping anomalous regions using simple heuristics. However, pixel grouping is a limiting factor when it comes to evaluating the segmentation performance of individual anomalous objects. To address the issue of grouping multiple anomaly instances into one, we propose an approach that produces accurate anomaly instance masks. Our approach centers on an out-of-distribution segmentation model for identifying uncertain regions and a strong generalist segmentation model for anomaly instances segmentation. We investigate ways to use uncertain regions to guide such a segmentation model to perform segmentation of anomalous instances. By incorporating strong object priors from a generalist model we additionally improve the per-pixel anomaly segmentation performance. Our approach outperforms current pixel-level anomaly segmentation methods, achieving an AP of 80.08% and 88.98% on the Fishyscapes Lost and Found and the RoadAnomaly validation sets respectively. Project page: https://vision.rwth-aachen.de/ugains

With the rapid development of computational pathology, many AI-assisted diagnostic tasks have emerged. Cellular nuclei segmentation can segment various types of cells for downstream analysis, but it relies on predefined categories and lacks flexibility. Moreover, pathology visual question answering can perform image-level understanding but lacks region-level detection capability. To address this, we propose a new benchmark called Pathology Visual Grounding (PathVG), which aims to detect regions based on expressions with different attributes. To evaluate PathVG, we create a new dataset named RefPath which contains 27,610 images with 33,500 language-grounded boxes. Compared to visual grounding in other domains, PathVG presents pathological images at multi-scale and contains expressions with pathological knowledge. In the experimental study, we found that the biggest challenge was the implicit information underlying the pathological expressions. Based on this, we proposed Pathology Knowledge-enhanced Network (PKNet) as the baseline model for PathVG. PKNet leverages the knowledge-enhancement capabilities of Large Language Models (LLMs) to convert pathological terms with implicit information into explicit visual features, and fuses knowledge features with expression features through the designed Knowledge Fusion Module (KFM). The proposed method achieves state-of-the-art performance on the PathVG benchmark.

Unsupervised learning poses one of the most difficult challenges in computer vision today. The task has an immense practical value with many applications in artificial intelligence and emerging technologies, as large quantities of unlabeled videos can be collected at relatively low cost. In this paper, we address the unsupervised learning problem in the context of detecting the main foreground objects in single images. We train a student deep network to predict the output of a teacher pathway that performs unsupervised object discovery in videos or large image collections. Our approach is different from published methods on unsupervised object discovery. We move the unsupervised learning phase during training time, then at test time we apply the standard feed-forward processing along the student pathway. This strategy has the benefit of allowing increased generalization possibilities during training, while remaining fast at testing. Our unsupervised learning algorithm can run over several generations of student-teacher training. Thus, a group of student networks trained in the first generation collectively create the teacher at the next generation. In experiments our method achieves top results on three current datasets for object discovery in video, unsupervised image segmentation and saliency detection. At test time the proposed system is fast, being one to two orders of magnitude faster than published unsupervised methods.

The reasoning segmentation task, which demands a nuanced comprehension of intricate queries to accurately pinpoint object regions, is attracting increasing attention. However, Multi-modal Large Language Models (MLLM) often find it difficult to accurately localize the objects described in complex reasoning contexts. We believe that the act of reasoning segmentation should mirror the cognitive stages of human visual search, where each step is a progressive refinement of thought toward the final object. Thus we introduce the Chains of Reasoning and Segmenting (CoReS) and find this top-down visual hierarchy indeed enhances the visual search process. Specifically, we propose a dual-chain structure that generates multi-modal, chain-like outputs to aid the segmentation process. Furthermore, to steer the MLLM's outputs into this intended hierarchy, we incorporate in-context inputs as guidance. Extensive experiments demonstrate the superior performance of our CoReS, which surpasses the state-of-the-art method by 6.5\% on the ReasonSeg dataset. Project: https://chain-of-reasoning-and-segmentation.github.io/.

The realm of computer vision has witnessed a paradigm shift with the advent of foundational models, mirroring the transformative influence of large language models in the domain of natural language processing. This paper delves into the exploration of open-world segmentation, presenting a novel approach called Image Prompt Segmentation (IPSeg) that harnesses the power of vision foundational models. IPSeg lies the principle of a training-free paradigm, which capitalizes on image prompt techniques. Specifically, IPSeg utilizes a single image containing a subjective visual concept as a flexible prompt to query vision foundation models like DINOv2 and Stable Diffusion. Our approach extracts robust features for the prompt image and input image, then matches the input representations to the prompt representations via a novel feature interaction module to generate point prompts highlighting target objects in the input image. The generated point prompts are further utilized to guide the Segment Anything Model to segment the target object in the input image. The proposed method stands out by eliminating the need for exhaustive training sessions, thereby offering a more efficient and scalable solution. Experiments on COCO, PASCAL VOC, and other datasets demonstrate IPSeg's efficacy for flexible open-world segmentation using intuitive image prompts. This work pioneers tapping foundation models for open-world understanding through visual concepts conveyed in images.

While state of the art image segmentation models typically output segmentations in raster format, applications in geographic information systems often require vector polygons. To help bridge the gap between deep network output and the format used in downstream tasks, we add a frame field output to a deep segmentation model for extracting buildings from remote sensing images. We train a deep neural network that aligns a predicted frame field to ground truth contours. This additional objective improves segmentation quality by leveraging multi-task learning and provides structural information that later facilitates polygonization; we also introduce a polygonization algorithm that utilizes the frame field along with the raster segmentation. Our code is available at https://github.com/Lydorn/Polygonization-by-Frame-Field-Learning.

We present a systematic study on a new task called dichotomous image segmentation (DIS) , which aims to segment highly accurate objects from natural images. To this end, we collected the first large-scale DIS dataset, called DIS5K, which contains 5,470 high-resolution (e.g., 2K, 4K or larger) images covering camouflaged, salient, or meticulous objects in various backgrounds. DIS is annotated with extremely fine-grained labels. Besides, we introduce a simple intermediate supervision baseline (IS-Net) using both feature-level and mask-level guidance for DIS model training. IS-Net outperforms various cutting-edge baselines on the proposed DIS5K, making it a general self-learned supervision network that can facilitate future research in DIS. Further, we design a new metric called human correction efforts (HCE) which approximates the number of mouse clicking operations required to correct the false positives and false negatives. HCE is utilized to measure the gap between models and real-world applications and thus can complement existing metrics. Finally, we conduct the largest-scale benchmark, evaluating 16 representative segmentation models, providing a more insightful discussion regarding object complexities, and showing several potential applications (e.g., background removal, art design, 3D reconstruction). Hoping these efforts can open up promising directions for both academic and industries. Project page: https://xuebinqin.github.io/dis/index.html.

Interactive segmentation enables users to segment as needed by providing cues of objects, which introduces human-computer interaction for many fields, such as image editing and medical image analysis. Typically, massive and expansive pixel-level annotations are spent to train deep models by object-oriented interactions with manually labeled object masks. In this work, we reveal that informative interactions can be made by simulation with semantic-consistent yet diverse region exploration in an unsupervised paradigm. Concretely, we introduce a Multi-granularity Interaction Simulation (MIS) approach to open up a promising direction for unsupervised interactive segmentation. Drawing on the high-quality dense features produced by recent self-supervised models, we propose to gradually merge patches or regions with similar features to form more extensive regions and thus, every merged region serves as a semantic-meaningful multi-granularity proposal. By randomly sampling these proposals and simulating possible interactions based on them, we provide meaningful interaction at multiple granularities to teach the model to understand interactions. Our MIS significantly outperforms non-deep learning unsupervised methods and is even comparable with some previous deep-supervised methods without any annotation.

Interactive segmentation of 3D Gaussians opens a great opportunity for real-time manipulation of 3D scenes thanks to the real-time rendering capability of 3D Gaussian Splatting. However, the current methods suffer from time-consuming post-processing to deal with noisy segmentation output. Also, they struggle to provide detailed segmentation, which is important for fine-grained manipulation of 3D scenes. In this study, we propose Click-Gaussian, which learns distinguishable feature fields of two-level granularity, facilitating segmentation without time-consuming post-processing. We delve into challenges stemming from inconsistently learned feature fields resulting from 2D segmentation obtained independently from a 3D scene. 3D segmentation accuracy deteriorates when 2D segmentation results across the views, primary cues for 3D segmentation, are in conflict. To overcome these issues, we propose Global Feature-guided Learning (GFL). GFL constructs the clusters of global feature candidates from noisy 2D segments across the views, which smooths out noises when training the features of 3D Gaussians. Our method runs in 10 ms per click, 15 to 130 times as fast as the previous methods, while also significantly improving segmentation accuracy. Our project page is available at https://seokhunchoi.github.io/Click-Gaussian

We introduce the Segment Anything (SA) project: a new task, model, and dataset for image segmentation. Using our efficient model in a data collection loop, we built the largest segmentation dataset to date (by far), with over 1 billion masks on 11M licensed and privacy respecting images. The model is designed and trained to be promptable, so it can transfer zero-shot to new image distributions and tasks. We evaluate its capabilities on numerous tasks and find that its zero-shot performance is impressive -- often competitive with or even superior to prior fully supervised results. We are releasing the Segment Anything Model (SAM) and corresponding dataset (SA-1B) of 1B masks and 11M images at https://segment-anything.com to foster research into foundation models for computer vision.

3D object part segmentation is essential in computer vision applications. While substantial progress has been made in 2D object part segmentation, the 3D counterpart has received less attention, in part due to the scarcity of annotated 3D datasets, which are expensive to collect. In this work, we propose to leverage a few annotated 3D shapes or richly annotated 2D datasets to perform 3D object part segmentation. We present our novel approach, termed 3-By-2 that achieves SOTA performance on different benchmarks with various granularity levels. By using features from pretrained foundation models and exploiting semantic and geometric correspondences, we are able to overcome the challenges of limited 3D annotations. Our approach leverages available 2D labels, enabling effective 3D object part segmentation. Our method 3-By-2 can accommodate various part taxonomies and granularities, demonstrating interesting part label transfer ability across different object categories. Project website: https://ngailapdi.github.io/projects/3by2/.

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data as pixels rather than interconnected structures. In biological structures, however, organs are not separate entities; for example, in reality, a severed vessel is an indication of an underlying problem, but traditional segmentation models are not designed to strictly enforce the continuity of anatomy, potentially leading to inaccurate medical diagnoses. To address this issue, we propose a graph-based approach that enforces the continuity and connectivity of anatomical topology in medical images. Our method encodes the continuity of shapes as a graph constraint, ensuring that the network's predictions maintain this continuity. We evaluate our method on two public benchmarks on retinal vessel segmentation, showing significant improvements in connectivity metrics compared to traditional methods while getting better or on-par performance on segmentation metrics.

Semantic segmentation has a broad range of applications, but its real-world impact has been significantly limited by the prohibitive annotation costs necessary to enable deployment. Segmentation methods that forgo supervision can side-step these costs, but exhibit the inconvenient requirement to provide labelled examples from the target distribution to assign concept names to predictions. An alternative line of work in language-image pre-training has recently demonstrated the potential to produce models that can both assign names across large vocabularies of concepts and enable zero-shot transfer for classification, but do not demonstrate commensurate segmentation abilities. In this work, we strive to achieve a synthesis of these two approaches that combines their strengths. We leverage the retrieval abilities of one such language-image pre-trained model, CLIP, to dynamically curate training sets from unlabelled images for arbitrary collections of concept names, and leverage the robust correspondences offered by modern image representations to co-segment entities among the resulting collections. The synthetic segment collections are then employed to construct a segmentation model (without requiring pixel labels) whose knowledge of concepts is inherited from the scalable pre-training process of CLIP. We demonstrate that our approach, termed Retrieve and Co-segment (ReCo) performs favourably to unsupervised segmentation approaches while inheriting the convenience of nameable predictions and zero-shot transfer. We also demonstrate ReCo's ability to generate specialist segmenters for extremely rare objects.

Diffusion models have recently received increasing research attention for their remarkable transfer abilities in semantic segmentation tasks. However, generating fine-grained segmentation masks with diffusion models often requires additional training on annotated datasets, leaving it unclear to what extent pre-trained diffusion models alone understand the semantic relations of their generated images. To address this question, we leverage the semantic knowledge extracted from Stable Diffusion (SD) and aim to develop an image segmentor capable of generating fine-grained segmentation maps without any additional training. The primary difficulty stems from the fact that semantically meaningful feature maps typically exist only in the spatially lower-dimensional layers, which poses a challenge in directly extracting pixel-level semantic relations from these feature maps. To overcome this issue, our framework identifies semantic correspondences between image pixels and spatial locations of low-dimensional feature maps by exploiting SD's generation process and utilizes them for constructing image-resolution segmentation maps. In extensive experiments, the produced segmentation maps are demonstrated to be well delineated and capture detailed parts of the images, indicating the existence of highly accurate pixel-level semantic knowledge in diffusion models.

Automatic identification of brain lesions from magnetic resonance imaging (MRI) scans of stroke survivors would be a useful aid in patient diagnosis and treatment planning. We propose a multi-modal multi-path convolutional neural network system for automating stroke lesion segmentation. Our system has nine end-to-end UNets that take as input 2-dimensional (2D) slices and examines all three planes with three different normalizations. Outputs from these nine total paths are concatenated into a 3D volume that is then passed to a 3D convolutional neural network to output a final lesion mask. We trained and tested our method on datasets from three sources: Medical College of Wisconsin (MCW), Kessler Foundation (KF), and the publicly available Anatomical Tracings of Lesions After Stroke (ATLAS) dataset. Cross-study validation results (with independent training and validation datasets) were obtained to compare with previous methods based on naive Bayes, random forests, and three recently published convolutional neural networks. Model performance was quantified in terms of the Dice coefficient. Training on the KF and MCW images and testing on the ATLAS images yielded a mean Dice coefficient of 0.54. This was reliably better than the next best previous model, UNet, at 0.47. Reversing the train and test datasets yields a mean Dice of 0.47 on KF and MCW images, whereas the next best UNet reaches 0.45. With all three datasets combined, the current system compared to previous methods also attained a reliably higher cross-validation accuracy. It also achieved high Dice values for many smaller lesions that existing methods have difficulty identifying. Overall, our system is a clear improvement over previous methods for automating stroke lesion segmentation, bringing us an important step closer to the inter-rater accuracy level of human experts.

The development of 2D foundation models for image segmentation has been significantly advanced by the Segment Anything Model (SAM). However, achieving similar success in 3D models remains a challenge due to issues such as non-unified data formats, lightweight models, and the scarcity of labeled data with diverse masks. To this end, we propose a 3D promptable segmentation model (Point-SAM) focusing on point clouds. Our approach utilizes a transformer-based method, extending SAM to the 3D domain. We leverage part-level and object-level annotations and introduce a data engine to generate pseudo labels from SAM, thereby distilling 2D knowledge into our 3D model. Our model outperforms state-of-the-art models on several indoor and outdoor benchmarks and demonstrates a variety of applications, such as 3D annotation. Codes and demo can be found at https://github.com/zyc00/Point-SAM.

Recent advances in methods focused on the grounding problem have resulted in techniques that can be used to construct a symbolic language associated with a specific domain. Inspired by how humans communicate complex ideas through language, we developed a generalized Symbolic Semantic (S^2) framework for interpretable segmentation. Unlike adversarial models (e.g., GANs), we explicitly model cooperation between two agents, a Sender and a Receiver, that must cooperate to achieve a common goal. The Sender receives information from a high layer of a segmentation network and generates a symbolic sentence derived from a categorical distribution. The Receiver obtains the symbolic sentences and co-generates the segmentation mask. In order for the model to converge, the Sender and Receiver must learn to communicate using a private language. We apply our architecture to segment tumors in the TCGA dataset. A UNet-like architecture is used to generate input to the Sender network which produces a symbolic sentence, and a Receiver network co-generates the segmentation mask based on the sentence. Our Segmentation framework achieved similar or better performance compared with state-of-the-art segmentation methods. In addition, our results suggest direct interpretation of the symbolic sentences to discriminate between normal and tumor tissue, tumor morphology, and other image characteristics.

Referring image segmentation, the task of segmenting any arbitrary entities described in free-form texts, opens up a variety of vision applications. However, manual labeling of training data for this task is prohibitively costly, leading to lack of labeled data for training. We address this issue by a weakly supervised learning approach using text descriptions of training images as the only source of supervision. To this end, we first present a new model that discovers semantic entities in input image and then combines such entities relevant to text query to predict the mask of the referent. We also present a new loss function that allows the model to be trained without any further supervision. Our method was evaluated on four public benchmarks for referring image segmentation, where it clearly outperformed the existing method for the same task and recent open-vocabulary segmentation models on all the benchmarks.

Open-world 3D part segmentation is pivotal in diverse applications such as robotics and AR/VR. Traditional supervised methods often grapple with limited 3D data availability and struggle to generalize to unseen object categories. PartSLIP, a recent advancement, has made significant strides in zero- and few-shot 3D part segmentation. This is achieved by harnessing the capabilities of the 2D open-vocabulary detection module, GLIP, and introducing a heuristic method for converting and lifting multi-view 2D bounding box predictions into 3D segmentation masks. In this paper, we introduce PartSLIP++, an enhanced version designed to overcome the limitations of its predecessor. Our approach incorporates two major improvements. First, we utilize a pre-trained 2D segmentation model, SAM, to produce pixel-wise 2D segmentations, yielding more precise and accurate annotations than the 2D bounding boxes used in PartSLIP. Second, PartSLIP++ replaces the heuristic 3D conversion process with an innovative modified Expectation-Maximization algorithm. This algorithm conceptualizes 3D instance segmentation as unobserved latent variables, and then iteratively refines them through an alternating process of 2D-3D matching and optimization with gradient descent. Through extensive evaluations, we show that PartSLIP++ demonstrates better performance over PartSLIP in both low-shot 3D semantic and instance-based object part segmentation tasks. Code released at https://github.com/zyc00/PartSLIP2.

Large-scale vision foundation models such as Segment Anything (SAM) demonstrate impressive performance in zero-shot image segmentation at multiple levels of granularity. However, these zero-shot predictions are rarely 3D-consistent. As the camera viewpoint changes in a scene, so do the segmentation predictions, as well as the characterizations of "coarse" or "fine" granularity. In this work, we address the challenging task of lifting multi-granular and view-inconsistent image segmentations into a hierarchical and 3D-consistent representation. We learn a novel feature field within a Neural Radiance Field (NeRF) representing a 3D scene, whose segmentation structure can be revealed at different scales by simply using different thresholds on feature distance. Our key idea is to learn an ultrametric feature space, which unlike a Euclidean space, exhibits transitivity in distance-based grouping, naturally leading to a hierarchical clustering. Put together, our method takes view-inconsistent multi-granularity 2D segmentations as input and produces a hierarchy of 3D-consistent segmentations as output. We evaluate our method and several baselines on synthetic datasets with multi-view images and multi-granular segmentation, showcasing improved accuracy and viewpoint-consistency. We additionally provide qualitative examples of our model's 3D hierarchical segmentations in real world scenes. The code and dataset are available at https://github.com/hardyho/ultrametric_feature_fields

Interactive Segmentation (IS) segments specific objects or parts in the image according to user input. Current IS pipelines fall into two categories: single-granularity output and multi-granularity output. The latter aims to alleviate the spatial ambiguity present in the former. However, the multi-granularity output pipeline suffers from limited interaction flexibility and produces redundant results. In this work, we introduce Granularity-Controllable Interactive Segmentation (GraCo), a novel approach that allows precise control of prediction granularity by introducing additional parameters to input. This enhances the customization of the interactive system and eliminates redundancy while resolving ambiguity. Nevertheless, the exorbitant cost of annotating multi-granularity masks and the lack of available datasets with granularity annotations make it difficult for models to acquire the necessary guidance to control output granularity. To address this problem, we design an any-granularity mask generator that exploits the semantic property of the pre-trained IS model to automatically generate abundant mask-granularity pairs without requiring additional manual annotation. Based on these pairs, we propose a granularity-controllable learning strategy that efficiently imparts the granularity controllability to the IS model. Extensive experiments on intricate scenarios at object and part levels demonstrate that our GraCo has significant advantages over previous methods. This highlights the potential of GraCo to be a flexible annotation tool, capable of adapting to diverse segmentation scenarios. The project page: https://zhao-yian.github.io/GraCo.

In this paper, we focus on image inpainting task, aiming at recovering the missing area of an incomplete image given the context information. Recent development in deep generative models enables an efficient end-to-end framework for image synthesis and inpainting tasks, but existing methods based on generative models don't exploit the segmentation information to constrain the object shapes, which usually lead to blurry results on the boundary. To tackle this problem, we propose to introduce the semantic segmentation information, which disentangles the inter-class difference and intra-class variation for image inpainting. This leads to much clearer recovered boundary between semantically different regions and better texture within semantically consistent segments. Our model factorizes the image inpainting process into segmentation prediction (SP-Net) and segmentation guidance (SG-Net) as two steps, which predict the segmentation labels in the missing area first, and then generate segmentation guided inpainting results. Experiments on multiple public datasets show that our approach outperforms existing methods in optimizing the image inpainting quality, and the interactive segmentation guidance provides possibilities for multi-modal predictions of image inpainting.

We consider the problem of segmenting objects in videos based on their motion and no other forms of supervision. Prior work has often approached this problem by using the principle of common fate, namely the fact that the motion of points that belong to the same object is strongly correlated. However, most authors have only considered instantaneous motion from optical flow. In this work, we present a way to train a segmentation network using long-term point trajectories as a supervisory signal to complement optical flow. The key difficulty is that long-term motion, unlike instantaneous motion, is difficult to model -- any parametric approximation is unlikely to capture complex motion patterns over long periods of time. We instead draw inspiration from subspace clustering approaches, proposing a loss function that seeks to group the trajectories into low-rank matrices where the motion of object points can be approximately explained as a linear combination of other point tracks. Our method outperforms the prior art on motion-based segmentation, which shows the utility of long-term motion and the effectiveness of our formulation.

Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps requires carefully curated post-processing, which is error-prone and parameter-sensitive. Recently, the Segment Anything Model (SAM) has earned huge attention in medical image segmentation, owing to its impressive generalization ability and promptable property. Nevertheless, its potential on nucleus instance segmentation remains largely underexplored. In this paper, we present a novel prompt-driven framework that consists of a nucleus prompter and SAM for automatic nucleus instance segmentation. Specifically, the prompter learns to generate a unique point prompt for each nucleus while the SAM is fine-tuned to output the corresponding mask for the prompted nucleus. Furthermore, we propose the inclusion of adjacent nuclei as negative prompts to enhance the model's capability to identify overlapping nuclei. Without complicated post-processing, our proposed method sets a new state-of-the-art performance on three challenging benchmarks. Code is available at github.com/windygoo/PromptNucSeg

Rotoscoping, the detailed delineation of scene elements through a video shot, is a painstaking task of tremendous importance in professional post-production pipelines. While pixel-wise segmentation techniques can help for this task, professional rotoscoping tools rely on parametric curves that offer the artists a much better interactive control on the definition, editing and manipulation of the segments of interest. Sticking to this prevalent rotoscoping paradigm, we propose a novel framework to capture and track the visual aspect of an arbitrary object in a scene, given a first closed outline of this object. This model combines a collection of local foreground/background appearance models spread along the outline, a global appearance model of the enclosed object and a set of distinctive foreground landmarks. The structure of this rich appearance model allows simple initialization, efficient iterative optimization with exact minimization at each step, and on-line adaptation in videos. We demonstrate qualitatively and quantitatively the merit of this framework through comparisons with tools based on either dynamic segmentation with a closed curve or pixel-wise binary labelling.

The objective of this paper is motion segmentation -- discovering and segmenting the moving objects in a video. This is a much studied area with numerous careful,and sometimes complex, approaches and training schemes including: self-supervised learning, learning from synthetic datasets, object-centric representations, amodal representations, and many more. Our interest in this paper is to determine if the Segment Anything model (SAM) can contribute to this task. We investigate two models for combining SAM with optical flow that harness the segmentation power of SAM with the ability of flow to discover and group moving objects. In the first model, we adapt SAM to take optical flow, rather than RGB, as an input. In the second, SAM takes RGB as an input, and flow is used as a segmentation prompt. These surprisingly simple methods, without any further modifications, outperform all previous approaches by a considerable margin in both single and multi-object benchmarks. We also extend these frame-level segmentations to sequence-level segmentations that maintain object identity. Again, this simple model outperforms previous methods on multiple video object segmentation benchmarks.

Segmentation of biomedical images can assist radiologists to make a better diagnosis and take decisions faster by helping in the detection of abnormalities, such as tumors. Manual or semi-automated segmentation, however, can be a time-consuming task. Most deep learning based automated segmentation methods are supervised and rely on manually segmented ground-truth. A possible solution for the problem would be an unsupervised deep learning based approach for automated segmentation, which this research work tries to address. We use a W-Net architecture and modified it, such that it can be applied to 3D volumes. In addition, to suppress noise in the segmentation we added attention gates to the skip connections. The loss for the segmentation output was calculated using soft N-Cuts and for the reconstruction output using SSIM. Conditional Random Fields were used as a post-processing step to fine-tune the results. The proposed method has shown promising results, with a dice coefficient of 0.88 for the liver segmentation compared against manual segmentation.

Foundation models have emerged as powerful tools across various domains including language, vision, and multimodal tasks. While prior works have addressed unsupervised image segmentation, they significantly lag behind supervised models. In this paper, we use a diffusion UNet encoder as a foundation vision encoder and introduce DiffCut, an unsupervised zero-shot segmentation method that solely harnesses the output features from the final self-attention block. Through extensive experimentation, we demonstrate that the utilization of these diffusion features in a graph based segmentation algorithm, significantly outperforms previous state-of-the-art methods on zero-shot segmentation. Specifically, we leverage a recursive Normalized Cut algorithm that softly regulates the granularity of detected objects and produces well-defined segmentation maps that precisely capture intricate image details. Our work highlights the remarkably accurate semantic knowledge embedded within diffusion UNet encoders that could then serve as foundation vision encoders for downstream tasks. Project page at https://diffcut-segmentation.github.io

The detailed images produced by Magnetic Resonance Imaging (MRI) provide life-critical information for the diagnosis and treatment of prostate cancer. To provide standardized acquisition, interpretation and usage of the complex MRI images, the PI-RADS v2 guideline was proposed. An automated segmentation following the guideline facilitates consistent and precise lesion detection, staging and treatment. The guideline recommends a division of the prostate into four zones, PZ (peripheral zone), TZ (transition zone), DPU (distal prostatic urethra) and AFS (anterior fibromuscular stroma). Not every zone shares a boundary with the others and is present in every slice. Further, the representations captured by a single model might not suffice for all zones. This motivated us to design a dual-branch convolutional neural network (CNN), where each branch captures the representations of the connected zones separately. Further, the representations from different branches act complementary to each other at the second stage of training, where they are fine-tuned through an unsupervised loss. The loss penalises the difference in predictions from the two branches for the same class. We also incorporate multi-task learning in our framework to further improve the segmentation accuracy. The proposed approach improves the segmentation accuracy of the baseline (mean absolute symmetric distance) by 7.56%, 11.00%, 58.43% and 19.67% for PZ, TZ, DPU and AFS zones respectively.

Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase commercial solutions. We present a code-free pipeline utilizing free-to-use, open-source software (QuPath, DeepMIB, and FastPathology) for creating and deploying deep learning-based segmentation models for computational pathology. We demonstrate the pipeline on a use case of separating epithelium from stroma in colonic mucosa. A dataset of 251 annotated WSIs, comprising 140 hematoxylin-eosin (HE)-stained and 111 CD3 immunostained colon biopsy WSIs, were developed through active learning using the pipeline. On a hold-out test set of 36 HE and 21 CD3-stained WSIs a mean intersection over union score of 96.6% and 95.3% was achieved on epithelium segmentation. We demonstrate pathologist-level segmentation accuracy and clinical acceptable runtime performance and show that pathologists without programming experience can create near state-of-the-art segmentation solutions for histopathological WSIs using only free-to-use software. The study further demonstrates the strength of open-source solutions in its ability to create generalizable, open pipelines, of which trained models and predictions can seamlessly be exported in open formats and thereby used in external solutions. All scripts, trained models, a video tutorial, and the full dataset of 251 WSIs with ~31k epithelium annotations are made openly available at https://github.com/andreped/NoCodeSeg to accelerate research in the field.

Vision transformer based models bring significant improvements for image segmentation tasks. Although these architectures offer powerful capabilities irrespective of specific segmentation tasks, their use of computational resources can be taxing on deployed devices. One way to overcome this challenge is by adapting the computation level to the specific needs of the input image rather than the current one-size-fits-all approach. To this end, we introduce ECO-M2F or EffiCient TransfOrmer Encoders for Mask2Former-style models. Noting that the encoder module of M2F-style models incur high resource-intensive computations, ECO-M2F provides a strategy to self-select the number of hidden layers in the encoder, conditioned on the input image. To enable this self-selection ability for providing a balance between performance and computational efficiency, we present a three step recipe. The first step is to train the parent architecture to enable early exiting from the encoder. The second step is to create an derived dataset of the ideal number of encoder layers required for each training example. The third step is to use the aforementioned derived dataset to train a gating network that predicts the number of encoder layers to be used, conditioned on the input image. Additionally, to change the computational-accuracy tradeoff, only steps two and three need to be repeated which significantly reduces retraining time. Experiments on the public datasets show that the proposed approach reduces expected encoder computational cost while maintaining performance, adapts to various user compute resources, is flexible in architecture configurations, and can be extended beyond the segmentation task to object detection.

Large Multimodal Models (LMMs) have achieved significant progress by extending large language models. Building on this progress, the latest developments in LMMs demonstrate the ability to generate dense pixel-wise segmentation through the integration of segmentation models.Despite the innovations, the textual responses and segmentation masks of existing works remain at the instance level, showing limited ability to perform fine-grained understanding and segmentation even provided with detailed textual cues.To overcome this limitation, we introduce a Multi-Granularity Large Multimodal Model (MGLMM), which is capable of seamlessly adjusting the granularity of Segmentation and Captioning (SegCap) following user instructions, from panoptic SegCap to fine-grained SegCap. We name such a new task Multi-Granularity Segmentation and Captioning (MGSC). Observing the lack of a benchmark for model training and evaluation over the MGSC task, we establish a benchmark with aligned masks and captions in multi-granularity using our customized automated annotation pipeline. This benchmark comprises 10K images and more than 30K image-question pairs. We will release our dataset along with the implementation of our automated dataset annotation pipeline for further research.Besides, we propose a novel unified SegCap data format to unify heterogeneous segmentation datasets; it effectively facilitates learning to associate object concepts with visual features during multi-task training. Extensive experiments demonstrate that our MGLMM excels at tackling more than eight downstream tasks and achieves state-of-the-art performance in MGSC, GCG, image captioning, referring segmentation, multiple and empty segmentation, and reasoning segmentation tasks. The great performance and versatility of MGLMM underscore its potential impact on advancing multimodal research.

Fairness is crucial when training a deep-learning discriminative model, especially in the facial domain. Models tend to correlate specific characteristics (such as age and skin color) with unrelated attributes (downstream tasks), resulting in biases which do not correspond to reality. It is common knowledge that these correlations are present in the data and are then transferred to the models during training. This paper proposes a method to mitigate these correlations to improve fairness. To do so, we learn interpretable and meaningful paths lying in the semantic space of a pre-trained diffusion model (DiffAE) -- such paths being supervised by contrastive text dipoles. That is, we learn to edit protected characteristics (age and skin color). These paths are then applied to augment images to improve the fairness of a given dataset. We test the proposed method on CelebA-HQ and UTKFace on several downstream tasks with age and skin color as protected characteristics. As a proxy for fairness, we compute the difference in accuracy with respect to the protected characteristics. Quantitative results show how the augmented images help the model improve the overall accuracy, the aforementioned metric, and the disparity of equal opportunity. Code is available at: https://github.com/Moreno98/Vision-Language-Bias-Control.

This work introduces a new framework, ProtoSAM, for one-shot medical image segmentation. It combines the use of prototypical networks, known for few-shot segmentation, with SAM - a natural image foundation model. The method proposed creates an initial coarse segmentation mask using the ALPnet prototypical network, augmented with a DINOv2 encoder. Following the extraction of an initial mask, prompts are extracted, such as points and bounding boxes, which are then input into the Segment Anything Model (SAM). State-of-the-art results are shown on several medical image datasets and demonstrate automated segmentation capabilities using a single image example (one shot) with no need for fine-tuning of the foundation model. Our code is available at: https://github.com/levayz/ProtoSAM

Towards holistic understanding of 3D scenes, a general 3D segmentation method is needed that can segment diverse objects without restrictions on object quantity or categories, while also reflecting the inherent hierarchical structure. To achieve this, we propose OmniSeg3D, an omniversal segmentation method aims for segmenting anything in 3D all at once. The key insight is to lift multi-view inconsistent 2D segmentations into a consistent 3D feature field through a hierarchical contrastive learning framework, which is accomplished by two steps. Firstly, we design a novel hierarchical representation based on category-agnostic 2D segmentations to model the multi-level relationship among pixels. Secondly, image features rendered from the 3D feature field are clustered at different levels, which can be further drawn closer or pushed apart according to the hierarchical relationship between different levels. In tackling the challenges posed by inconsistent 2D segmentations, this framework yields a global consistent 3D feature field, which further enables hierarchical segmentation, multi-object selection, and global discretization. Extensive experiments demonstrate the effectiveness of our method on high-quality 3D segmentation and accurate hierarchical structure understanding. A graphical user interface further facilitates flexible interaction for omniversal 3D segmentation.

Segment Anything Model (SAM) has gained significant attention because of its ability to segment a variety of objects in images given a prompt. The recently developed SAM 2 has extended this ability to video inputs. This opens an opportunity to apply SAM to 3D images, one of the fundamental tasks in the medical imaging field. In this paper, we provide an extensive evaluation of SAM 2's ability to segment both 2D and 3D medical images. We collect 18 medical imaging datasets, including common 3D modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) as well as 2D modalities such as X-ray and ultrasound. We consider two evaluation pipelines of SAM 2: (1) multi-frame 3D segmentation, where prompts are provided to one or multiple slice(s) selected from the volume, and (2) single-frame 2D segmentation, where prompts are provided to each slice. The former is only applicable to 3D modalities, while the latter applies to both 2D and 3D modalities. We learn that SAM 2 exhibits similar performance as SAM under single-frame 2D segmentation, and has variable performance under multi-frame 3D segmentation depending on the choices of slices to annotate, the direction of the propagation, the predictions utilized during the propagation, etc.

Panoptic segmentation methods assign a known class to each pixel given in input. Even for state-of-the-art approaches, this inevitably enforces decisions that systematically lead to wrong predictions for objects outside the training categories. However, robustness against out-of-distribution samples and corner cases is crucial in safety-critical settings to avoid dangerous consequences. Since real-world datasets cannot contain enough data points to adequately sample the long tail of the underlying distribution, models must be able to deal with unseen and unknown scenarios as well. Previous methods targeted this by re-identifying already-seen unlabeled objects. In this work, we propose the necessary step to extend segmentation with a new setting which we term holistic segmentation. Holistic segmentation aims to identify and separate objects of unseen, unknown categories into instances without any prior knowledge about them while performing panoptic segmentation of known classes. We tackle this new problem with U3HS, which finds unknowns as highly uncertain regions and clusters their corresponding instance-aware embeddings into individual objects. By doing so, for the first time in panoptic segmentation with unknown objects, our U3HS is trained without unknown categories, reducing assumptions and leaving the settings as unconstrained as in real-life scenarios. Extensive experiments on public data from MS COCO, Cityscapes, and Lost&Found demonstrate the effectiveness of U3HS for this new, challenging, and assumptions-free setting called holistic segmentation. Project page: https://holisticseg.github.io.

Click-based interactive segmentation (IS) aims to extract the target objects under user interaction. For this task, most of the current deep learning (DL)-based methods mainly follow the general pipelines of semantic segmentation. Albeit achieving promising performance, they do not fully and explicitly utilize and propagate the click information, inevitably leading to unsatisfactory segmentation results, even at clicked points. Against this issue, in this paper, we propose to formulate the IS task as a Gaussian process (GP)-based pixel-wise binary classification model on each image. To solve this model, we utilize amortized variational inference to approximate the intractable GP posterior in a data-driven manner and then decouple the approximated GP posterior into double space forms for efficient sampling with linear complexity. Then, we correspondingly construct a GP classification framework, named GPCIS, which is integrated with the deep kernel learning mechanism for more flexibility. The main specificities of the proposed GPCIS lie in: 1) Under the explicit guidance of the derived GP posterior, the information contained in clicks can be finely propagated to the entire image and then boost the segmentation; 2) The accuracy of predictions at clicks has good theoretical support. These merits of GPCIS as well as its good generality and high efficiency are substantiated by comprehensive experiments on several benchmarks, as compared with representative methods both quantitatively and qualitatively.

We aim to tackle the problem of point-based interactive segmentation, in which the key challenge is to propagate the user-provided annotations to unlabeled regions efficiently. Existing methods tackle this challenge by utilizing computationally expensive fully connected graphs or transformer architectures that sacrifice important fine-grained information required for accurate segmentation. To overcome these limitations, we propose a cascade sparse feature propagation network that learns a click-augmented feature representation for propagating user-provided information to unlabeled regions. The sparse design of our network enables efficient information propagation on high-resolution features, resulting in more detailed object segmentation. We validate the effectiveness of our method through comprehensive experiments on various benchmarks, and the results demonstrate the superior performance of our approach. Code is available at https://github.com/kleinzcy/CSFPN{https://github.com/kleinzcy/CSFPN}.

Unsupervised 3D instance segmentation aims to segment objects from a 3D point cloud without any annotations. Existing methods face the challenge of either too loose or too tight clustering, leading to under-segmentation or over-segmentation. To address this issue, we propose Part2Object, hierarchical clustering with object guidance. Part2Object employs multi-layer clustering from points to object parts and objects, allowing objects to manifest at any layer. Additionally, it extracts and utilizes 3D objectness priors from temporally consecutive 2D RGB frames to guide the clustering process. Moreover, we propose Hi-Mask3D to support hierarchical 3D object part and instance segmentation. By training Hi-Mask3D on the objects and object parts extracted from Part2Object, we achieve consistent and superior performance compared to state-of-the-art models in various settings, including unsupervised instance segmentation, data-efficient fine-tuning, and cross-dataset generalization. Code is release at https://github.com/ChengShiest/Part2Object

Curating datasets for object segmentation is a difficult task. With the advent of large-scale pre-trained generative models, conditional image generation has been given a significant boost in result quality and ease of use. In this paper, we present a novel method that enables the generation of general foreground-background segmentation models from simple textual descriptions, without requiring segmentation labels. We leverage and explore pre-trained latent diffusion models, to automatically generate weak segmentation masks for concepts and objects. The masks are then used to fine-tune the diffusion model on an inpainting task, which enables fine-grained removal of the object, while at the same time providing a synthetic foreground and background dataset. We demonstrate that using this method beats previous methods in both discriminative and generative performance and closes the gap with fully supervised training while requiring no pixel-wise object labels. We show results on the task of segmenting four different objects (humans, dogs, cars, birds) and a use case scenario in medical image analysis. The code is available at https://github.com/MischaD/fobadiffusion.

In recent years, concept-based approaches have emerged as some of the most promising explainability methods to help us interpret the decisions of Artificial Neural Networks (ANNs). These methods seek to discover intelligible visual 'concepts' buried within the complex patterns of ANN activations in two key steps: (1) concept extraction followed by (2) importance estimation. While these two steps are shared across methods, they all differ in their specific implementations. Here, we introduce a unifying theoretical framework that comprehensively defines and clarifies these two steps. This framework offers several advantages as it allows us: (i) to propose new evaluation metrics for comparing different concept extraction approaches; (ii) to leverage modern attribution methods and evaluation metrics to extend and systematically evaluate state-of-the-art concept-based approaches and importance estimation techniques; (iii) to derive theoretical guarantees regarding the optimality of such methods. We further leverage our framework to try to tackle a crucial question in explainability: how to efficiently identify clusters of data points that are classified based on a similar shared strategy. To illustrate these findings and to highlight the main strategies of a model, we introduce a visual representation called the strategic cluster graph. Finally, we present https://serre-lab.github.io/Lens, a dedicated website that offers a complete compilation of these visualizations for all classes of the ImageNet dataset.

Diffusion models have demonstrated remarkable progress in image generation quality, especially when guidance is used to control the generative process. However, guidance requires a large amount of image-annotation pairs for training and is thus dependent on their availability, correctness and unbiasedness. In this paper, we eliminate the need for such annotation by instead leveraging the flexibility of self-supervision signals to design a framework for self-guided diffusion models. By leveraging a feature extraction function and a self-annotation function, our method provides guidance signals at various image granularities: from the level of holistic images to object boxes and even segmentation masks. Our experiments on single-label and multi-label image datasets demonstrate that self-labeled guidance always outperforms diffusion models without guidance and may even surpass guidance based on ground-truth labels, especially on unbalanced data. When equipped with self-supervised box or mask proposals, our method further generates visually diverse yet semantically consistent images, without the need for any class, box, or segment label annotation. Self-guided diffusion is simple, flexible and expected to profit from deployment at scale. Source code will be at: https://taohu.me/sgdm/

We demonstrate two novel editing procedures in the context of fantasy card art. Palette transfer applies a specified reference palette to a given card. For fantasy art, the desired change in palette can be very large, leading to huge changes in the "look" of the art. We demonstrate that a pipeline of vector quantization; matching; and "vector dequantization" (using a diffusion model) produces successful extreme palette transfers. Segment control allows an artist to move one or more image segments, and to optionally specify the desired color of the result. The combination of these two types of edit yields valuable workflows, including: move a segment, then recolor; recolor, then force some segments to take a prescribed color. We demonstrate our methods on the challenging Yu-Gi-Oh card art dataset.

Object segmentation is an important step in the workflow of computational pathology. Deep learning based models generally require large amount of labeled data for precise and reliable prediction. However, collecting labeled data is expensive because it often requires expert knowledge, particularly in medical imaging domain where labels are the result of a time-consuming analysis made by one or more human experts. As nuclei, cells and glands are fundamental objects for downstream analysis in computational pathology/cytology, in this paper we propose a simple CNN-based approach to speed up collecting annotations for these objects which requires minimum interaction from the annotator. We show that for nuclei and cells in histology and cytology images, one click inside each object is enough for NuClick to yield a precise annotation. For multicellular structures such as glands, we propose a novel approach to provide the NuClick with a squiggle as a guiding signal, enabling it to segment the glandular boundaries. These supervisory signals are fed to the network as auxiliary inputs along with RGB channels. With detailed experiments, we show that NuClick is adaptable to the object scale, robust against variations in the user input, adaptable to new domains, and delivers reliable annotations. An instance segmentation model trained on masks generated by NuClick achieved the first rank in LYON19 challenge. As exemplar outputs of our framework, we are releasing two datasets: 1) a dataset of lymphocyte annotations within IHC images, and 2) a dataset of segmented WBCs in blood smear images.

Task-generic promptable image segmentation aims to achieve segmentation of diverse samples under a single task description by utilizing only one task-generic prompt. Current methods leverage the generalization capabilities of Vision-Language Models (VLMs) to infer instance-specific prompts from these task-generic prompts in order to guide the segmentation process. However, when VLMs struggle to generalise to some image instances, predicting instance-specific prompts becomes poor. To solve this problem, we introduce Instance-specific Negative Mining for Task-Generic Promptable Segmentation (INT). The key idea of INT is to adaptively reduce the influence of irrelevant (negative) prior knowledge whilst to increase the use the most plausible prior knowledge, selected by negative mining with higher contrast, in order to optimise instance-specific prompts generation. Specifically, INT consists of two components: (1) instance-specific prompt generation, which progressively fliters out incorrect information in prompt generation; (2) semantic mask generation, which ensures each image instance segmentation matches correctly the semantics of the instance-specific prompts. INT is validated on six datasets, including camouflaged objects and medical images, demonstrating its effectiveness, robustness and scalability.

Fiber tractography is a cornerstone of neuroimaging, enabling the detailed mapping of the brain's white matter pathways through diffusion MRI. This is crucial for understanding brain connectivity and function, making it a valuable tool in neurological applications. Despite its importance, tractography faces challenges due to its complexity and susceptibility to false positives, misrepresenting vital pathways. To address these issues, recent strategies have shifted towards deep learning, utilizing supervised learning, which depends on precise ground truth, or reinforcement learning, which operates without it. In this work, we propose Tract-RLFormer, a network utilizing both supervised and reinforcement learning, in a two-stage policy refinement process that markedly improves the accuracy and generalizability across various data-sets. By employing a tract-specific approach, our network directly delineates the tracts of interest, bypassing the traditional segmentation process. Through rigorous validation on datasets such as TractoInferno, HCP, and ISMRM-2015, our methodology demonstrates a leap forward in tractography, showcasing its ability to accurately map the brain's white matter tracts.

The general domain of video segmentation is currently fragmented into different tasks spanning multiple benchmarks. Despite rapid progress in the state-of-the-art, current methods are overwhelmingly task-specific and cannot conceptually generalize to other tasks. Inspired by recent approaches with multi-task capability, we propose TarViS: a novel, unified network architecture that can be applied to any task that requires segmenting a set of arbitrarily defined 'targets' in video. Our approach is flexible with respect to how tasks define these targets, since it models the latter as abstract 'queries' which are then used to predict pixel-precise target masks. A single TarViS model can be trained jointly on a collection of datasets spanning different tasks, and can hot-swap between tasks during inference without any task-specific retraining. To demonstrate its effectiveness, we apply TarViS to four different tasks, namely Video Instance Segmentation (VIS), Video Panoptic Segmentation (VPS), Video Object Segmentation (VOS) and Point Exemplar-guided Tracking (PET). Our unified, jointly trained model achieves state-of-the-art performance on 5/7 benchmarks spanning these four tasks, and competitive performance on the remaining two. Code and model weights are available at: https://github.com/Ali2500/TarViS

Analysis of 3D segmentation models, especially in the context of medical imaging, is often limited to segmentation performance metrics that overlook the crucial aspect of explainability and bias. Currently, effectively explaining these models with saliency maps is challenging due to the high dimensions of input images multiplied by the ever-growing number of segmented class labels. To this end, we introduce Agg^2Exp, a methodology for aggregating fine-grained voxel attributions of the segmentation model's predictions. Unlike classical explanation methods that primarily focus on the local feature attribution, Agg^2Exp enables a more comprehensive global view on the importance of predicted segments in 3D images. Our benchmarking experiments show that gradient-based voxel attributions are more faithful to the model's predictions than perturbation-based explanations. As a concrete use-case, we apply Agg^2Exp to discover knowledge acquired by the Swin UNEt TRansformer model trained on the TotalSegmentator v2 dataset for segmenting anatomical structures in computed tomography medical images. Agg^2Exp facilitates the explanatory analysis of large segmentation models beyond their predictive performance.

Weakly-Supervised Semantic Segmentation (WSSS) aims to train segmentation models using image data with only image-level supervision. Since precise pixel-level annotations are not accessible, existing methods typically focus on producing pseudo masks for training segmentation models by refining CAM-like heatmaps. However, the produced heatmaps may capture only the discriminative image regions of object categories or the associated co-occurring backgrounds. To address the issues, we propose a Semantic Prompt Learning for WSSS (SemPLeS) framework, which learns to effectively prompt the CLIP latent space to enhance the semantic alignment between the segmented regions and the target object categories. More specifically, we propose Contrastive Prompt Learning and Prompt-guided Semantic Refinement to learn the prompts that adequately describe and suppress the co-occurring backgrounds associated with each target object category. In this way, SemPLeS can perform better semantic alignment between object regions and the associated class labels, resulting in desired pseudo masks for training the segmentation model. The proposed SemPLeS framework achieves SOTA performance on the standard WSSS benchmarks, PASCAL VOC and MS COCO, and shows compatibility with other WSSS methods. The source codes are provided in the supplementary.

White matter tract segmentation is crucial for studying brain structural connectivity and neurosurgical planning. However, segmentation remains challenging due to issues like class imbalance between major and minor tracts, structural similarity, subject variability, symmetric streamlines between hemispheres etc. To address these challenges, we propose TractoEmbed, a modular multi-level embedding framework, that encodes localized representations through learning tasks in respective encoders. In this paper, TractoEmbed introduces a novel hierarchical streamline data representation that captures maximum spatial information at each level i.e. individual streamlines, clusters, and patches. Experiments show that TractoEmbed outperforms state-of-the-art methods in white matter tract segmentation across different datasets, and spanning various age groups. The modular framework directly allows the integration of additional embeddings in future works.

In the diverse field of medical imaging, automatic segmentation has numerous applications and must handle a wide variety of input domains, such as different types of Computed Tomography (CT) scans and Magnetic Resonance (MR) images. This heterogeneity challenges automatic segmentation algorithms to maintain consistent performance across different modalities due to the requirement for spatially aligned and paired images. Typically, segmentation models are trained using a single modality, which limits their ability to generalize to other types of input data without employing transfer learning techniques. Additionally, leveraging complementary information from different modalities to enhance segmentation precision often necessitates substantial modifications to popular encoder-decoder designs, such as introducing multiple branched encoding or decoding paths for each modality. In this work, we propose a simple Multi-Modal Segmentation (MulModSeg) strategy to enhance medical image segmentation across multiple modalities, specifically CT and MR. It incorporates two key designs: a modality-conditioned text embedding framework via a frozen text encoder that adds modality awareness to existing segmentation frameworks without significant structural modifications or computational overhead, and an alternating training procedure that facilitates the integration of essential features from unpaired CT and MR inputs. Through extensive experiments with both Fully Convolutional Network and Transformer-based backbones, MulModSeg consistently outperforms previous methods in segmenting abdominal multi-organ and cardiac substructures for both CT and MR modalities. The code is available in this {https://github.com/ChengyinLee/MulModSeg_2024{link}}.

The recently proposed segment anything model (SAM) has made a significant influence in many computer vision tasks. It is becoming a foundation step for many high-level tasks, like image segmentation, image caption, and image editing. However, its huge computation costs prevent it from wider applications in industry scenarios. The computation mainly comes from the Transformer architecture at high-resolution inputs. In this paper, we propose a speed-up alternative method for this fundamental task with comparable performance. By reformulating the task as segments-generation and prompting, we find that a regular CNN detector with an instance segmentation branch can also accomplish this task well. Specifically, we convert this task to the well-studied instance segmentation task and directly train the existing instance segmentation method using only 1/50 of the SA-1B dataset published by SAM authors. With our method, we achieve a comparable performance with the SAM method at 50 times higher run-time speed. We give sufficient experimental results to demonstrate its effectiveness. The codes and demos will be released at https://github.com/CASIA-IVA-Lab/FastSAM.

The goal of this paper is to extract the visual-language correspondence from a pre-trained text-to-image diffusion model, in the form of segmentation map, i.e., simultaneously generating images and segmentation masks for the corresponding visual entities described in the text prompt. We make the following contributions: (i) we pair the existing Stable Diffusion model with a novel grounding module, that can be trained to align the visual and textual embedding space of the diffusion model with only a small number of object categories; (ii) we establish an automatic pipeline for constructing a dataset, that consists of {image, segmentation mask, text prompt} triplets, to train the proposed grounding module; (iii) we evaluate the performance of open-vocabulary grounding on images generated from the text-to-image diffusion model and show that the module can well segment the objects of categories beyond seen ones at training time; (iv) we adopt the augmented diffusion model to build a synthetic semantic segmentation dataset, and show that, training a standard segmentation model on such dataset demonstrates competitive performance on the zero-shot segmentation(ZS3) benchmark, which opens up new opportunities for adopting the powerful diffusion model for discriminative tasks.

We present Segment Anything Model 2 (SAM 2), a foundation model towards solving promptable visual segmentation in images and videos. We build a data engine, which improves model and data via user interaction, to collect the largest video segmentation dataset to date. Our model is a simple transformer architecture with streaming memory for real-time video processing. SAM 2 trained on our data provides strong performance across a wide range of tasks. In video segmentation, we observe better accuracy, using 3x fewer interactions than prior approaches. In image segmentation, our model is more accurate and 6x faster than the Segment Anything Model (SAM). We believe that our data, model, and insights will serve as a significant milestone for video segmentation and related perception tasks. We are releasing a version of our model, the dataset and an interactive demo.

Recent advancements in 3D perception systems have significantly improved their ability to perform visual recognition tasks such as segmentation. However, these systems still heavily rely on explicit human instruction to identify target objects or categories, lacking the capability to actively reason and comprehend implicit user intentions. We introduce a novel segmentation task known as reasoning part segmentation for 3D objects, aiming to output a segmentation mask based on complex and implicit textual queries about specific parts of a 3D object. To facilitate evaluation and benchmarking, we present a large 3D dataset comprising over 60k instructions paired with corresponding ground-truth part segmentation annotations specifically curated for reasoning-based 3D part segmentation. We propose a model that is capable of segmenting parts of 3D objects based on implicit textual queries and generating natural language explanations corresponding to 3D object segmentation requests. Experiments show that our method achieves competitive performance to models that use explicit queries, with the additional abilities to identify part concepts, reason about them, and complement them with world knowledge. Our source code, dataset, and trained models are available at https://github.com/AmrinKareem/PARIS3D.

Open-world entity segmentation, as an emerging computer vision task, aims at segmenting entities in images without being restricted by pre-defined classes, offering impressive generalization capabilities on unseen images and concepts. Despite its promise, existing entity segmentation methods like Segment Anything Model (SAM) rely heavily on costly expert annotators. This work presents Self-supervised Open-world Hierarchical Entity Segmentation (SOHES), a novel approach that eliminates the need for human annotations. SOHES operates in three phases: self-exploration, self-instruction, and self-correction. Given a pre-trained self-supervised representation, we produce abundant high-quality pseudo-labels through visual feature clustering. Then, we train a segmentation model on the pseudo-labels, and rectify the noises in pseudo-labels via a teacher-student mutual-learning procedure. Beyond segmenting entities, SOHES also captures their constituent parts, providing a hierarchical understanding of visual entities. Using raw images as the sole training data, our method achieves unprecedented performance in self-supervised open-world segmentation, marking a significant milestone towards high-quality open-world entity segmentation in the absence of human-annotated masks. Project page: https://SOHES.github.io.

FSS(Few-shot segmentation) aims to segment a target class using a small number of labeled images (support set). To extract the information relevant to target class, a dominant approach in best performing FSS methods removes background features using a support mask. We observe that this feature excision through a limiting support mask introduces an information bottleneck in several challenging FSS cases, e.g., for small targets and/or inaccurate target boundaries. To this end, we present a novel method (MSI), which maximizes the support-set information by exploiting two complementary sources of features to generate super correlation maps. We validate the effectiveness of our approach by instantiating it into three recent and strong FSS methods. Experimental results on several publicly available FSS benchmarks show that our proposed method consistently improves the performance by visible margins and leads to faster convergence. Our code and models will be publicly released.

There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the available annotated samples more efficiently. The architecture consists of a contracting path to capture context and a symmetric expanding path that enables precise localization. We show that such a network can be trained end-to-end from very few images and outperforms the prior best method (a sliding-window convolutional network) on the ISBI challenge for segmentation of neuronal structures in electron microscopic stacks. Using the same network trained on transmitted light microscopy images (phase contrast and DIC) we won the ISBI cell tracking challenge 2015 in these categories by a large margin. Moreover, the network is fast. Segmentation of a 512x512 image takes less than a second on a recent GPU. The full implementation (based on Caffe) and the trained networks are available at http://lmb.informatik.uni-freiburg.de/people/ronneber/u-net .

We study learning object segmentation from unlabeled videos. Humans can easily segment moving objects without knowing what they are. The Gestalt law of common fate, i.e., what move at the same speed belong together, has inspired unsupervised object discovery based on motion segmentation. However, common fate is not a reliable indicator of objectness: Parts of an articulated / deformable object may not move at the same speed, whereas shadows / reflections of an object always move with it but are not part of it. Our insight is to bootstrap objectness by first learning image features from relaxed common fate and then refining them based on visual appearance grouping within the image itself and across images statistically. Specifically, we learn an image segmenter first in the loop of approximating optical flow with constant segment flow plus small within-segment residual flow, and then by refining it for more coherent appearance and statistical figure-ground relevance. On unsupervised video object segmentation, using only ResNet and convolutional heads, our model surpasses the state-of-the-art by absolute gains of 7/9/5% on DAVIS16 / STv2 / FBMS59 respectively, demonstrating the effectiveness of our ideas. Our code is publicly available.

Open-vocabulary image segmentation aims to partition an image into semantic regions according to arbitrary text descriptions. However, complex visual scenes can be naturally decomposed into simpler parts and abstracted at multiple levels of granularity, introducing inherent segmentation ambiguity. Unlike existing methods that typically sidestep this ambiguity and treat it as an external factor, our approach actively incorporates a hierarchical representation encompassing different semantic-levels into the learning process. We propose a decoupled text-image fusion mechanism and representation learning modules for both "things" and "stuff". Additionally, we systematically examine the differences that exist in the textual and visual features between these types of categories. Our resulting model, named HIPIE, tackles HIerarchical, oPen-vocabulary, and unIvErsal segmentation tasks within a unified framework. Benchmarked on over 40 datasets, e.g., ADE20K, COCO, Pascal-VOC Part, RefCOCO/RefCOCOg, ODinW and SeginW, HIPIE achieves the state-of-the-art results at various levels of image comprehension, including semantic-level (e.g., semantic segmentation), instance-level (e.g., panoptic/referring segmentation and object detection), as well as part-level (e.g., part/subpart segmentation) tasks. Our code is released at https://github.com/berkeley-hipie/HIPIE.

Most state-of-the-art instance segmentation methods rely on large amounts of pixel-precise ground-truth annotations for training, which are expensive to create. Interactive segmentation networks help generate such annotations based on an image and the corresponding user interactions such as clicks. Existing methods for this task can only process a single instance at a time and each user interaction requires a full forward pass through the entire deep network. We introduce a more efficient approach, called DynaMITe, in which we represent user interactions as spatio-temporal queries to a Transformer decoder with a potential to segment multiple object instances in a single iteration. Our architecture also alleviates any need to re-compute image features during refinement, and requires fewer interactions for segmenting multiple instances in a single image when compared to other methods. DynaMITe achieves state-of-the-art results on multiple existing interactive segmentation benchmarks, and also on the new multi-instance benchmark that we propose in this paper.

Training data for video segmentation are expensive to annotate. This impedes extensions of end-to-end algorithms to new video segmentation tasks, especially in large-vocabulary settings. To 'track anything' without training on video data for every individual task, we develop a decoupled video segmentation approach (DEVA), composed of task-specific image-level segmentation and class/task-agnostic bi-directional temporal propagation. Due to this design, we only need an image-level model for the target task (which is cheaper to train) and a universal temporal propagation model which is trained once and generalizes across tasks. To effectively combine these two modules, we use bi-directional propagation for (semi-)online fusion of segmentation hypotheses from different frames to generate a coherent segmentation. We show that this decoupled formulation compares favorably to end-to-end approaches in several data-scarce tasks including large-vocabulary video panoptic segmentation, open-world video segmentation, referring video segmentation, and unsupervised video object segmentation. Code is available at: https://hkchengrex.github.io/Tracking-Anything-with-DEVA

Universal Image Segmentation is not a new concept. Past attempts to unify image segmentation in the last decades include scene parsing, panoptic segmentation, and, more recently, new panoptic architectures. However, such panoptic architectures do not truly unify image segmentation because they need to be trained individually on the semantic, instance, or panoptic segmentation to achieve the best performance. Ideally, a truly universal framework should be trained only once and achieve SOTA performance across all three image segmentation tasks. To that end, we propose OneFormer, a universal image segmentation framework that unifies segmentation with a multi-task train-once design. We first propose a task-conditioned joint training strategy that enables training on ground truths of each domain (semantic, instance, and panoptic segmentation) within a single multi-task training process. Secondly, we introduce a task token to condition our model on the task at hand, making our model task-dynamic to support multi-task training and inference. Thirdly, we propose using a query-text contrastive loss during training to establish better inter-task and inter-class distinctions. Notably, our single OneFormer model outperforms specialized Mask2Former models across all three segmentation tasks on ADE20k, CityScapes, and COCO, despite the latter being trained on each of the three tasks individually with three times the resources. With new ConvNeXt and DiNAT backbones, we observe even more performance improvement. We believe OneFormer is a significant step towards making image segmentation more universal and accessible. To support further research, we open-source our code and models at https://github.com/SHI-Labs/OneFormer

Amodal object segmentation is a challenging task that involves segmenting both visible and occluded parts of an object. In this paper, we propose a novel approach, called Coarse-to-Fine Segmentation (C2F-Seg), that addresses this problem by progressively modeling the amodal segmentation. C2F-Seg initially reduces the learning space from the pixel-level image space to the vector-quantized latent space. This enables us to better handle long-range dependencies and learn a coarse-grained amodal segment from visual features and visible segments. However, this latent space lacks detailed information about the object, which makes it difficult to provide a precise segmentation directly. To address this issue, we propose a convolution refine module to inject fine-grained information and provide a more precise amodal object segmentation based on visual features and coarse-predicted segmentation. To help the studies of amodal object segmentation, we create a synthetic amodal dataset, named as MOViD-Amodal (MOViD-A), which can be used for both image and video amodal object segmentation. We extensively evaluate our model on two benchmark datasets: KINS and COCO-A. Our empirical results demonstrate the superiority of C2F-Seg. Moreover, we exhibit the potential of our approach for video amodal object segmentation tasks on FISHBOWL and our proposed MOViD-A. Project page at: http://jianxgao.github.io/C2F-Seg.

During interactive segmentation, a model and a user work together to delineate objects of interest in a 3D point cloud. In an iterative process, the model assigns each data point to an object (or the background), while the user corrects errors in the resulting segmentation and feeds them back into the model. The current best practice formulates the problem as binary classification and segments objects one at a time. The model expects the user to provide positive clicks to indicate regions wrongly assigned to the background and negative clicks on regions wrongly assigned to the object. Sequentially visiting objects is wasteful since it disregards synergies between objects: a positive click for a given object can, by definition, serve as a negative click for nearby objects. Moreover, a direct competition between adjacent objects can speed up the identification of their common boundary. We introduce AGILE3D, an efficient, attention-based model that (1) supports simultaneous segmentation of multiple 3D objects, (2) yields more accurate segmentation masks with fewer user clicks, and (3) offers faster inference. Our core idea is to encode user clicks as spatial-temporal queries and enable explicit interactions between click queries as well as between them and the 3D scene through a click attention module. Every time new clicks are added, we only need to run a lightweight decoder that produces updated segmentation masks. In experiments with four different 3D point cloud datasets, AGILE3D sets a new state-of-the-art. Moreover, we also verify its practicality in real-world setups with real user studies.

Recently, "visual o1" began to enter people's vision, with expectations that this slow-thinking design can solve visual reasoning tasks, especially geometric math problems. However, the reality is that current LVLMs (Large Vision Language Models) can hardly even accurately copy a geometric figure, let alone truly understand the complex inherent logic and spatial relationships within geometric shapes. We believe accurate copying (strong perception) is the first step to visual o1. Accordingly, we introduce the concept of "slow perception" (SP), which guides the model to gradually perceive basic point-line combinations, as our humans, reconstruct complex geometric structures progressively. There are two-fold stages in SP: a) perception decomposition. Perception is not instantaneous. In this stage, complex geometric figures are broken down into basic simple units to unify geometry representation. b) perception flow, which acknowledges that accurately tracing a line is not an easy task. This stage aims to avoid "long visual jumps" in regressing line segments by using a proposed "perceptual ruler" to trace each line stroke-by-stroke. Surprisingly, such a human-like perception manner enjoys an inference time scaling law -- the slower, the better. Researchers strive to speed up the model's perception in the past, but we slow it down again, allowing the model to read the image step-by-step and carefully.

The emergence of large models, also known as foundation models, has brought significant advancements to AI research. One such model is Segment Anything (SAM), which is designed for image segmentation tasks. However, as with other foundation models, our experimental findings suggest that SAM may fail or perform poorly in certain segmentation tasks, such as shadow detection and camouflaged object detection (concealed object detection). This study first paves the way for applying the large pre-trained image segmentation model SAM to these downstream tasks, even in situations where SAM performs poorly. Rather than fine-tuning the SAM network, we propose SAM-Adapter, which incorporates domain-specific information or visual prompts into the segmentation network by using simple yet effective adapters. By integrating task-specific knowledge with general knowledge learnt by the large model, SAM-Adapter can significantly elevate the performance of SAM in challenging tasks as shown in extensive experiments. We can even outperform task-specific network models and achieve state-of-the-art performance in the task we tested: camouflaged object detection, shadow detection. We also tested polyp segmentation (medical image segmentation) and achieves better results. We believe our work opens up opportunities for utilizing SAM in downstream tasks, with potential applications in various fields, including medical image processing, agriculture, remote sensing, and more.

Rapid advancements in medical image segmentation performance have been significantly driven by the development of Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs). These models follow the discriminative pixel-wise classification learning paradigm and often have limited ability to generalize across diverse medical imaging datasets. In this manuscript, we introduce Generative Medical Segmentation (GMS), a novel approach leveraging a generative model to perform image segmentation. Concretely, GMS employs a robust pre-trained vision foundation model to extract latent representations for images and corresponding ground truth masks, followed by a model that learns a mapping function from the image to the mask in the latent space. Once trained, the model generates an estimated segmentation mask using the pre-trained vision foundation model to decode the predicted latent representation back into the image space. The design of GMS leads to fewer trainable parameters in the model which reduces the risk of overfitting and enhances its generalization capability. Our experimental analysis across five public datasets in different medical imaging domains demonstrates GMS outperforms existing discriminative and generative segmentation models. Furthermore, GMS is able to generalize well across datasets from different centers within the same imaging modality. Our experiments suggest GMS offers a scalable and effective solution for medical image segmentation. GMS implementation and trained model weights are available at https://github.com/King-HAW/GMS.

The caliber and configuration of retinal blood vessels serve as important biomarkers for various diseases and medical conditions. A thorough analysis of the retinal vasculature requires the segmentation of the blood vessels and their classification into arteries and veins, typically performed on color fundus images obtained by retinography. However, manually performing these tasks is labor-intensive and prone to human error. While several automated methods have been proposed to address this task, the current state of art faces challenges due to manifest classification errors affecting the topological consistency of segmentation maps. In this work, we introduce RRWNet, a novel end-to-end deep learning framework that addresses this limitation. The framework consists of a fully convolutional neural network that recursively refines semantic segmentation maps, correcting manifest classification errors and thus improving topological consistency. In particular, RRWNet is composed of two specialized subnetworks: a Base subnetwork that generates base segmentation maps from the input images, and a Recursive Refinement subnetwork that iteratively and recursively improves these maps. Evaluation on three different public datasets demonstrates the state-of-the-art performance of the proposed method, yielding more topologically consistent segmentation maps with fewer manifest classification errors than existing approaches. In addition, the Recursive Refinement module within RRWNet proves effective in post-processing segmentation maps from other methods, further demonstrating its potential. The model code, weights, and predictions will be publicly available at https://github.com/j-morano/rrwnet.

Interactive segmentation methods rely on user inputs to iteratively update the selection mask. A click specifying the object of interest is arguably the most simple and intuitive interaction type, and thereby the most common choice for interactive segmentation. However, user clicking patterns in the interactive segmentation context remain unexplored. Accordingly, interactive segmentation evaluation strategies rely more on intuition and common sense rather than empirical studies (e.g., assuming that users tend to click in the center of the area with the largest error). In this work, we conduct a real user study to investigate real user clicking patterns. This study reveals that the intuitive assumption made in the common evaluation strategy may not hold. As a result, interactive segmentation models may show high scores in the standard benchmarks, but it does not imply that they would perform well in a real world scenario. To assess the applicability of interactive segmentation methods, we propose a novel evaluation strategy providing a more comprehensive analysis of a model's performance. To this end, we propose a methodology for finding extreme user inputs by a direct optimization in a white-box adversarial attack on the interactive segmentation model. Based on the performance with such adversarial user inputs, we assess the robustness of interactive segmentation models w.r.t click positions. Besides, we introduce a novel benchmark for measuring the robustness of interactive segmentation, and report the results of an extensive evaluation of dozens of models.

Referring image segmentation aims to segment the target object referred by a natural language expression. However, previous methods rely on the strong assumption that one sentence must describe one target in the image, which is often not the case in real-world applications. As a result, such methods fail when the expressions refer to either no objects or multiple objects. In this paper, we address this issue from two perspectives. First, we propose a Dual Multi-Modal Interaction (DMMI) Network, which contains two decoder branches and enables information flow in two directions. In the text-to-image decoder, text embedding is utilized to query the visual feature and localize the corresponding target. Meanwhile, the image-to-text decoder is implemented to reconstruct the erased entity-phrase conditioned on the visual feature. In this way, visual features are encouraged to contain the critical semantic information about target entity, which supports the accurate segmentation in the text-to-image decoder in turn. Secondly, we collect a new challenging but realistic dataset called Ref-ZOM, which includes image-text pairs under different settings. Extensive experiments demonstrate our method achieves state-of-the-art performance on different datasets, and the Ref-ZOM-trained model performs well on various types of text inputs. Codes and datasets are available at https://github.com/toggle1995/RIS-DMMI.

The crux of label-efficient semantic segmentation is to produce high-quality pseudo-labels to leverage a large amount of unlabeled or weakly labeled data. A common practice is to select the highly confident predictions as the pseudo-ground-truths for each pixel, but it leads to a problem that most pixels may be left unused due to their unreliability. However, we argue that every pixel matters to the model training, even those unreliable and ambiguous pixels. Intuitively, an unreliable prediction may get confused among the top classes, however, it should be confident about the pixel not belonging to the remaining classes. Hence, such a pixel can be convincingly treated as a negative key to those most unlikely categories. Therefore, we develop an effective pipeline to make sufficient use of unlabeled data. Concretely, we separate reliable and unreliable pixels via the entropy of predictions, push each unreliable pixel to a category-wise queue that consists of negative keys, and manage to train the model with all candidate pixels. Considering the training evolution, we adaptively adjust the threshold for the reliable-unreliable partition. Experimental results on various benchmarks and training settings demonstrate the superiority of our approach over the state-of-the-art alternatives.

This paper introduces a network for volumetric segmentation that learns from sparsely annotated volumetric images. We outline two attractive use cases of this method: (1) In a semi-automated setup, the user annotates some slices in the volume to be segmented. The network learns from these sparse annotations and provides a dense 3D segmentation. (2) In a fully-automated setup, we assume that a representative, sparsely annotated training set exists. Trained on this data set, the network densely segments new volumetric images. The proposed network extends the previous u-net architecture from Ronneberger et al. by replacing all 2D operations with their 3D counterparts. The implementation performs on-the-fly elastic deformations for efficient data augmentation during training. It is trained end-to-end from scratch, i.e., no pre-trained network is required. We test the performance of the proposed method on a complex, highly variable 3D structure, the Xenopus kidney, and achieve good results for both use cases.

Curvilinear object segmentation plays a crucial role across various applications, yet datasets in this domain often suffer from small scale due to the high costs associated with data acquisition and annotation. To address these challenges, this paper introduces a novel approach for expanding curvilinear object segmentation datasets, focusing on enhancing the informativeness of generated data and the consistency between semantic maps and generated images. Our method enriches synthetic data informativeness by generating curvilinear objects through their multiple textual features. By combining textual features from each sample in original dataset, we obtain synthetic images that beyond the original dataset's distribution. This initiative necessitated the creation of the Curvilinear Object Segmentation based on Text Generation (COSTG) dataset. Designed to surpass the limitations of conventional datasets, COSTG incorporates not only standard semantic maps but also some textual descriptions of curvilinear object features. To ensure consistency between synthetic semantic maps and images, we introduce the Semantic Consistency Preserving ControlNet (SCP ControlNet). This involves an adaptation of ControlNet with Spatially-Adaptive Normalization (SPADE), allowing it to preserve semantic information that would typically be washed away in normalization layers. This modification facilitates more accurate semantic image synthesis. Experimental results demonstrate the efficacy of our approach across three types of curvilinear objects (angiography, crack and retina) and six public datasets (CHUAC, XCAD, DCA1, DRIVE, CHASEDB1 and Crack500). The synthetic data generated by our method not only expand the dataset, but also effectively improves the performance of other curvilinear object segmentation models. Source code and dataset are available at https://github.com/tanlei0/COSTG.

Segment Anything Model (SAM) is a foundation model for interactive segmentation, and it has catalyzed major advances in generative AI, computational photography, and medical imaging. This model takes in an arbitrary user input and provides segmentation masks of the corresponding objects. It is our goal to develop a version of SAM that is appropriate for use in a photography app. The original SAM model has a few challenges in this setting. First, original SAM a 600 million parameter based on ViT-H, and its high computational cost and large model size that are not suitable for todays mobile hardware. We address this by proposing the SqueezeSAM model architecture, which is 50x faster and 100x smaller than SAM. Next, when a user takes a photo on their phone, it might not occur to them to click on the image and get a mask. Our solution is to use salient object detection to generate the first few clicks. This produces an initial segmentation mask that the user can interactively edit. Finally, when a user clicks on an object, they typically expect all related pieces of the object to be segmented. For instance, if a user clicks on a person t-shirt in a photo, they expect the whole person to be segmented, but SAM typically segments just the t-shirt. We address this with a new data augmentation scheme, and the end result is that if the user clicks on a person holding a basketball, the person and the basketball are all segmented together.

In semantic segmentation, generalizing a visual system to both seen categories and novel categories at inference time has always been practically valuable yet challenging. To enable such functionality, existing methods mainly rely on either providing several support demonstrations from the visual aspect or characterizing the informative clues from the textual aspect (e.g., the class names). Nevertheless, both two lines neglect the complementary intrinsic of low-level visual and high-level language information, while the explorations that consider visual and textual modalities as a whole to promote predictions are still limited. To close this gap, we propose to encompass textual and visual clues as multi-modal prototypes to allow more comprehensive support for open-world semantic segmentation, and build a novel prototype-based segmentation framework to realize this promise. To be specific, unlike the straightforward combination of bi-modal clues, we decompose the high-level language information as multi-aspect prototypes and aggregate the low-level visual information as more semantic prototypes, on basis of which, a fine-grained complementary fusion makes the multi-modal prototypes more powerful and accurate to promote the prediction. Based on an elastic mask prediction module that permits any number and form of prototype inputs, we are able to solve the zero-shot, few-shot and generalized counterpart tasks in one architecture. Extensive experiments on both PASCAL-5^i and COCO-20^i datasets show the consistent superiority of the proposed method compared with the previous state-of-the-art approaches, and a range of ablation studies thoroughly dissects each component in our framework both quantitatively and qualitatively that verify their effectiveness.

Learning anatomical segmentation from heterogeneous labels in multi-center datasets is a common situation encountered in clinical scenarios, where certain anatomical structures are only annotated in images coming from particular medical centers, but not in the full database. Here we first show how state-of-the-art pixel-level segmentation models fail in naively learning this task due to domain memorization issues and conflicting labels. We then propose to adopt HybridGNet, a landmark-based segmentation model which learns the available anatomical structures using graph-based representations. By analyzing the latent space learned by both models, we show that HybridGNet naturally learns more domain-invariant feature representations, and provide empirical evidence in the context of chest X-ray multiclass segmentation. We hope these insights will shed light on the training of deep learning models with heterogeneous labels from public and multi-center datasets.

Translating images from a source domain to a target domain for learning target models is one of the most common strategies in domain adaptive semantic segmentation (DASS). However, existing methods still struggle to preserve semantically-consistent local details between the original and translated images. In this work, we present an innovative approach that addresses this challenge by using source-domain labels as explicit guidance during image translation. Concretely, we formulate cross-domain image translation as a denoising diffusion process and utilize a novel Semantic Gradient Guidance (SGG) method to constrain the translation process, conditioning it on the pixel-wise source labels. Additionally, a Progressive Translation Learning (PTL) strategy is devised to enable the SGG method to work reliably across domains with large gaps. Extensive experiments demonstrate the superiority of our approach over state-of-the-art methods.

Panoptic segmentation assigns semantic and instance ID labels to every pixel of an image. As permutations of instance IDs are also valid solutions, the task requires learning of high-dimensional one-to-many mapping. As a result, state-of-the-art approaches use customized architectures and task-specific loss functions. We formulate panoptic segmentation as a discrete data generation problem, without relying on inductive bias of the task. A diffusion model is proposed to model panoptic masks, with a simple architecture and generic loss function. By simply adding past predictions as a conditioning signal, our method is capable of modeling video (in a streaming setting) and thereby learns to track object instances automatically. With extensive experiments, we demonstrate that our simple approach can perform competitively to state-of-the-art specialist methods in similar settings.

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of unlabeled data can be unreliable, uncertainty-aware schemes are typically employed to gradually learn from meaningful and reliable predictions. Uncertainty estimation methods, however, rely on multiple inferences from the model predictions that must be computed for each training step, which is computationally expensive. Moreover, these uncertainty maps capture pixel-wise disparities and do not consider global information. This work proposes a novel method to estimate segmentation uncertainty by leveraging global information from the segmentation masks. More precisely, an anatomically-aware representation is first learnt to model the available segmentation masks. The learnt representation thereupon maps the prediction of a new segmentation into an anatomically-plausible segmentation. The deviation from the plausible segmentation aids in estimating the underlying pixel-level uncertainty in order to further guide the segmentation network. The proposed method consequently estimates the uncertainty using a single inference from our representation, thereby reducing the total computation. We evaluate our method on two publicly available segmentation datasets of left atria in cardiac MRIs and of multiple organs in abdominal CTs. Our anatomically-aware method improves the segmentation accuracy over the state-of-the-art semi-supervised methods in terms of two commonly used evaluation metrics.

Few-shot segmentation is the problem of learning to identify specific types of objects (e.g., airplanes) in images from a small set of labeled reference images. The current state of the art is driven by resource-intensive construction of models for every new domain-specific application. Such models must be trained on enormous labeled datasets of unrelated objects (e.g., cars, trains, animals) so that their ``knowledge'' can be transferred to new types of objects. In this paper, we show how to leverage existing vision foundation models (VFMs) to reduce the incremental cost of creating few-shot segmentation models for new domains. Specifically, we introduce SAMIC, a small network that learns how to prompt VFMs in order to segment new types of objects in domain-specific applications. SAMIC enables any task to be approached as a few-shot learning problem. At 2.6 million parameters, it is 94% smaller than the leading models (e.g., having ResNet 101 backbone with 45+ million parameters). Even using 1/5th of the training data provided by one-shot benchmarks, SAMIC is competitive with, or sets the state of the art, on a variety of few-shot and semantic segmentation datasets including COCO-20^i, Pascal-5^i, PerSeg, FSS-1000, and NWPU VHR-10.

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyperparameters in different experimental settings. Here, we present a multi-modality cell segmentation benchmark, comprising over 1500 labeled images derived from more than 50 diverse biological experiments. The top participants developed a Transformer-based deep-learning algorithm that not only exceeds existing methods, but can also be applied to diverse microscopy images across imaging platforms and tissue types without manual parameter adjustments. This benchmark and the improved algorithm offer promising avenues for more accurate and versatile cell analysis in microscopy imaging.

Semantic Segmentation is a significant research field in Computer Vision. Despite being a widely studied subject area, many visualization tools do not exist that capture segmentation quality and dataset statistics such as a class imbalance in the same view. While the significance of discovering and introspecting the correlation between dataset statistics and AI model performance for dense prediction computer vision tasks such as semantic segmentation is well established in the computer vision literature, to the best of our knowledge, no visualization tools have been proposed to view and analyze the aforementioned tasks. Our project aims to bridge this gap by proposing three visualizations that enable users to compare dataset statistics and AI performance for segmenting all images, a single image in the dataset, explore the AI model's attention on image regions once trained and browse the quality of masks predicted by AI for any selected (by user) number of objects under the same tool. Our project tries to further increase the interpretability of the trained AI model for segmentation by visualizing its image attention weights. For visualization, we use Scatterplot and Heatmap to encode correlation and features, respectively. We further propose to conduct surveys on real users to study the efficacy of our visualization tool in computer vision and AI domain. The full system can be accessed at https://github.com/dipta007/SeeBel

Plant diseases pose significant threats to agriculture. It necessitates proper diagnosis and effective treatment to safeguard crop yields. To automate the diagnosis process, image segmentation is usually adopted for precisely identifying diseased regions, thereby advancing precision agriculture. Developing robust image segmentation models for plant diseases demands high-quality annotations across numerous images. However, existing plant disease datasets typically lack segmentation labels and are often confined to controlled laboratory settings, which do not adequately reflect the complexity of natural environments. Motivated by this fact, we established PlantSeg, a large-scale segmentation dataset for plant diseases. PlantSeg distinguishes itself from existing datasets in three key aspects. (1) Annotation type: Unlike the majority of existing datasets that only contain class labels or bounding boxes, each image in PlantSeg includes detailed and high-quality segmentation masks, associated with plant types and disease names. (2) Image source: Unlike typical datasets that contain images from laboratory settings, PlantSeg primarily comprises in-the-wild plant disease images. This choice enhances the practical applicability, as the trained models can be applied for integrated disease management. (3) Scale: PlantSeg is extensive, featuring 11,400 images with disease segmentation masks and an additional 8,000 healthy plant images categorized by plant type. Extensive technical experiments validate the high quality of PlantSeg's annotations. This dataset not only allows researchers to evaluate their image classification methods but also provides a critical foundation for developing and benchmarking advanced plant disease segmentation algorithms.

To improve the prognosis of patients suffering from pulmonary diseases, such as lung cancer, early diagnosis and treatment are crucial. The analysis of CT images is invaluable for diagnosis, whereas high quality segmentation of the airway tree are required for intervention planning and live guidance during bronchoscopy. Recently, the Multi-domain Airway Tree Modeling (ATM'22) challenge released a large dataset, both enabling training of deep-learning based models and bringing substantial improvement of the state-of-the-art for the airway segmentation task. However, the ATM'22 dataset includes few patients with severe pathologies affecting the airway tree anatomy. In this study, we introduce a new public benchmark dataset (AeroPath), consisting of 27 CT images from patients with pathologies ranging from emphysema to large tumors, with corresponding trachea and bronchi annotations. Second, we present a multiscale fusion design for automatic airway segmentation. Models were trained on the ATM'22 dataset, tested on the AeroPath dataset, and further evaluated against competitive open-source methods. The same performance metrics as used in the ATM'22 challenge were used to benchmark the different considered approaches. Lastly, an open web application is developed, to easily test the proposed model on new data. The results demonstrated that our proposed architecture predicted topologically correct segmentations for all the patients included in the AeroPath dataset. The proposed method is robust and able to handle various anomalies, down to at least the fifth airway generation. In addition, the AeroPath dataset, featuring patients with challenging pathologies, will contribute to development of new state-of-the-art methods. The AeroPath dataset and the web application are made openly available.

We propose and study a task we name panoptic segmentation (PS). Panoptic segmentation unifies the typically distinct tasks of semantic segmentation (assign a class label to each pixel) and instance segmentation (detect and segment each object instance). The proposed task requires generating a coherent scene segmentation that is rich and complete, an important step toward real-world vision systems. While early work in computer vision addressed related image/scene parsing tasks, these are not currently popular, possibly due to lack of appropriate metrics or associated recognition challenges. To address this, we propose a novel panoptic quality (PQ) metric that captures performance for all classes (stuff and things) in an interpretable and unified manner. Using the proposed metric, we perform a rigorous study of both human and machine performance for PS on three existing datasets, revealing interesting insights about the task. The aim of our work is to revive the interest of the community in a more unified view of image segmentation.

In this paper, we introduce a novel knowledge distillation approach for the semantic segmentation task. Unlike previous methods that rely on power-trained teachers or other modalities to provide additional knowledge, our approach does not require complex teacher models or information from extra sensors. Specifically, for the teacher model training, we propose to noise the label and then incorporate it into input to effectively boost the lightweight teacher performance. To ensure the robustness of the teacher model against the introduced noise, we propose a dual-path consistency training strategy featuring a distance loss between the outputs of two paths. For the student model training, we keep it consistent with the standard distillation for simplicity. Our approach not only boosts the efficacy of knowledge distillation but also increases the flexibility in selecting teacher and student models. To demonstrate the advantages of our Label Assisted Distillation (LAD) method, we conduct extensive experiments on five challenging datasets including Cityscapes, ADE20K, PASCAL-VOC, COCO-Stuff 10K, and COCO-Stuff 164K, five popular models: FCN, PSPNet, DeepLabV3, STDC, and OCRNet, and results show the effectiveness and generalization of our approach. We posit that incorporating labels into the input, as demonstrated in our work, will provide valuable insights into related fields. Code is available at https://github.com/skyshoumeng/Label_Assisted_Distillation.

With the growing popularity of personalized human content creation and sharing, there is a rising demand for advanced techniques in customized human image generation. However, current methods struggle to simultaneously maintain the fidelity of human identity and ensure the consistency of textual prompts, often resulting in suboptimal outcomes. This shortcoming is primarily due to the lack of effective constraints during the simultaneous integration of visual and textual prompts, leading to unhealthy mutual interference that compromises the full expression of both types of input. Building on prior research that suggests visual and textual conditions influence different regions of an image in distinct ways, we introduce a novel Dual-Pathway Adapter (DP-Adapter) to enhance both high-fidelity identity preservation and textual consistency in personalized human image generation. Our approach begins by decoupling the target human image into visually sensitive and text-sensitive regions. For visually sensitive regions, DP-Adapter employs an Identity-Enhancing Adapter (IEA) to preserve detailed identity features. For text-sensitive regions, we introduce a Textual-Consistency Adapter (TCA) to minimize visual interference and ensure the consistency of textual semantics. To seamlessly integrate these pathways, we develop a Fine-Grained Feature-Level Blending (FFB) module that efficiently combines hierarchical semantic features from both pathways, resulting in more natural and coherent synthesis outcomes. Additionally, DP-Adapter supports various innovative applications, including controllable headshot-to-full-body portrait generation, age editing, old-photo to reality, and expression editing.

Recent advances in segmentation foundation models have enabled accurate and efficient segmentation across a wide range of natural images and videos, but their utility to medical data remains unclear. In this work, we first present a comprehensive benchmarking of the Segment Anything Model 2 (SAM2) across 11 medical image modalities and videos and point out its strengths and weaknesses by comparing it to SAM1 and MedSAM. Then, we develop a transfer learning pipeline and demonstrate SAM2 can be quickly adapted to medical domain by fine-tuning. Furthermore, we implement SAM2 as a 3D slicer plugin and Gradio API for efficient 3D image and video segmentation. The code has been made publicly available at https://github.com/bowang-lab/MedSAM.

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a redundant use of information, where similar low-level features are extracted multiple times at multiple scales. Second, long-range feature dependencies are not efficiently modeled, resulting in non-optimal discriminative feature representations associated with each semantic class. In this paper we attempt to overcome these limitations with the proposed architecture, by capturing richer contextual dependencies based on the use of guided self-attention mechanisms. This approach is able to integrate local features with their corresponding global dependencies, as well as highlight interdependent channel maps in an adaptive manner. Further, the additional loss between different modules guides the attention mechanisms to neglect irrelevant information and focus on more discriminant regions of the image by emphasizing relevant feature associations. We evaluate the proposed model in the context of semantic segmentation on three different datasets: abdominal organs, cardiovascular structures and brain tumors. A series of ablation experiments support the importance of these attention modules in the proposed architecture. In addition, compared to other state-of-the-art segmentation networks our model yields better segmentation performance, increasing the accuracy of the predictions while reducing the standard deviation. This demonstrates the efficiency of our approach to generate precise and reliable automatic segmentations of medical images. Our code is made publicly available at https://github.com/sinAshish/Multi-Scale-Attention

Scene parsing, or recognizing and segmenting objects and stuff in an image, is one of the key problems in computer vision. Despite the community's efforts in data collection, there are still few image datasets covering a wide range of scenes and object categories with dense and detailed annotations for scene parsing. In this paper, we introduce and analyze the ADE20K dataset, spanning diverse annotations of scenes, objects, parts of objects, and in some cases even parts of parts. A generic network design called Cascade Segmentation Module is then proposed to enable the segmentation networks to parse a scene into stuff, objects, and object parts in a cascade. We evaluate the proposed module integrated within two existing semantic segmentation networks, yielding significant improvements for scene parsing. We further show that the scene parsing networks trained on ADE20K can be applied to a wide variety of scenes and objects.

Recently, the tokens of images share the same static data flow in many dense networks. However, challenges arise from the variance among the objects in images, such as large variations in the spatial scale and difficulties of recognition for visual entities. In this paper, we propose a data-dependent token routing strategy to elaborate the routing paths of image tokens for Dynamic Vision Transformer, dubbed DiT. The proposed framework generates a data-dependent path per token, adapting to the object scales and visual discrimination of tokens. In feed-forward, the differentiable routing gates are designed to select the scaling paths and feature transformation paths for image tokens, leading to multi-path feature propagation. In this way, the impact of object scales and visual discrimination of image representation can be carefully tuned. Moreover, the computational cost can be further reduced by giving budget constraints to the routing gate and early-stopping of feature extraction. In experiments, our DiT achieves superior performance and favorable complexity/accuracy trade-offs than many SoTA methods on ImageNet classification, object detection, instance segmentation, and semantic segmentation. Particularly, the DiT-B5 obtains 84.8\% top-1 Acc on ImageNet with 10.3 GFLOPs, which is 1.0\% higher than that of the SoTA method with similar computational complexity. These extensive results demonstrate that DiT can serve as versatile backbones for various vision tasks.

Active contour models have achieved prominent success in the area of image segmentation, allowing complex objects to be segmented from the background for further analysis. Existing models can be divided into region-based active contour models and edge-based active contour models. However, both models use direct image data to achieve segmentation and face many challenging problems in terms of the initial contour position, noise sensitivity, local minima and inefficiency owing to the in-homogeneity of image intensities. The saliency map of an image changes the image representation, making it more visual and meaningful. In this study, we propose a novel model that uses the advantages of a saliency map with local image information (LIF) and overcomes the drawbacks of previous models. The proposed model is driven by a saliency map of an image and the local image information to enhance the progress of the active contour models. In this model, the saliency map of an image is first computed to find the saliency driven local fitting energy. Then, the saliency-driven local fitting energy is combined with the LIF model, resulting in a final novel energy functional. This final energy functional is formulated through a level set formulation, and regulation terms are added to evolve the contour more precisely across the object boundaries. The quality of the proposed method was verified on different synthetic images, real images and publicly available datasets, including medical images. The image segmentation results, and quantitative comparisons confirmed the contour initialization independence, noise insensitivity, and superior segmentation accuracy of the proposed model in comparison to the other segmentation models.

This work tackles scene understanding for outdoor robotic navigation, solely relying on images captured by an on-board camera. Conventional visual scene understanding interprets the environment based on specific descriptive categories. However, such a representation is not directly interpretable for decision-making and constrains robot operation to a specific domain. Thus, we propose to segment egocentric images directly in terms of how a robot can navigate in them, and tailor the learning problem to an autonomous navigation task. Building around an image segmentation network, we present a generic affordance consisting of 3 driveability levels which can broadly apply to both urban and off-road scenes. By encoding these levels with soft ordinal labels, we incorporate inter-class distances during learning which improves segmentation compared to standard "hard" one-hot labelling. In addition, we propose a navigation-oriented pixel-wise loss weighting method which assigns higher importance to safety-critical areas. We evaluate our approach on large-scale public image segmentation datasets ranging from sunny city streets to snowy forest trails. In a cross-dataset generalization experiment, we show that our affordance learning scheme can be applied across a diverse mix of datasets and improves driveability estimation in unseen environments compared to general-purpose, single-dataset segmentation.

In healthcare, medical image segmentation is crucial for accurate disease diagnosis and the development of effective treatment strategies. Early detection can significantly aid in managing diseases and potentially prevent their progression. Machine learning, particularly deep convolutional neural networks, has emerged as a promising approach to addressing segmentation challenges. Traditional methods like U-Net use encoding blocks for local representation modeling and decoding blocks to uncover semantic relationships. However, these models often struggle with multi-scale objects exhibiting significant variations in texture and shape, and they frequently fail to capture long-range dependencies in the input data. Transformers designed for sequence-to-sequence predictions have been proposed as alternatives, utilizing global self-attention mechanisms. Yet, they can sometimes lack precise localization due to insufficient granular details. To overcome these limitations, we introduce TransDAE: a novel approach that reimagines the self-attention mechanism to include both spatial and channel-wise associations across the entire feature space, while maintaining computational efficiency. Additionally, TransDAE enhances the skip connection pathway with an inter-scale interaction module, promoting feature reuse and improving localization accuracy. Remarkably, TransDAE outperforms existing state-of-the-art methods on the Synaps multi-organ dataset, even without relying on pre-trained weights.

A map, as crucial information for downstream applications of an autonomous driving system, is usually represented in lanelines or centerlines. However, existing literature on map learning primarily focuses on either detecting geometry-based lanelines or perceiving topology relationships of centerlines. Both of these methods ignore the intrinsic relationship of lanelines and centerlines, that lanelines bind centerlines. While simply predicting both types of lane in one model is mutually excluded in learning objective, we advocate lane segment as a new representation that seamlessly incorporates both geometry and topology information. Thus, we introduce LaneSegNet, the first end-to-end mapping network generating lane segments to obtain a complete representation of the road structure. Our algorithm features two key modifications. One is a lane attention module to capture pivotal region details within the long-range feature space. Another is an identical initialization strategy for reference points, which enhances the learning of positional priors for lane attention. On the OpenLane-V2 dataset, LaneSegNet outperforms previous counterparts by a substantial gain across three tasks, i.e., map element detection (+4.8 mAP), centerline perception (+6.9 DET_l), and the newly defined one, lane segment perception (+5.6 mAP). Furthermore, it obtains a real-time inference speed of 14.7 FPS. Code is accessible at https://github.com/OpenDriveLab/LaneSegNet.

Several unsupervised image segmentation approaches have been proposed which eliminate the need for dense manually-annotated segmentation masks; current models separately handle either semantic segmentation (e.g., STEGO) or class-agnostic instance segmentation (e.g., CutLER), but not both (i.e., panoptic segmentation). We propose an Unsupervised Universal Segmentation model (U2Seg) adept at performing various image segmentation tasks -- instance, semantic and panoptic -- using a novel unified framework. U2Seg generates pseudo semantic labels for these segmentation tasks via leveraging self-supervised models followed by clustering; each cluster represents different semantic and/or instance membership of pixels. We then self-train the model on these pseudo semantic labels, yielding substantial performance gains over specialized methods tailored to each task: a +2.6 AP^{box} boost vs. CutLER in unsupervised instance segmentation on COCO and a +7.0 PixelAcc increase (vs. STEGO) in unsupervised semantic segmentation on COCOStuff. Moreover, our method sets up a new baseline for unsupervised panoptic segmentation, which has not been previously explored. U2Seg is also a strong pretrained model for few-shot segmentation, surpassing CutLER by +5.0 AP^{mask} when trained on a low-data regime, e.g., only 1% COCO labels. We hope our simple yet effective method can inspire more research on unsupervised universal image segmentation.

Recent advances in text-to-video generation have demonstrated the utility of powerful diffusion models. Nevertheless, the problem is not trivial when shaping diffusion models to animate static image (i.e., image-to-video generation). The difficulty originates from the aspect that the diffusion process of subsequent animated frames should not only preserve the faithful alignment with the given image but also pursue temporal coherence among adjacent frames. To alleviate this, we present TRIP, a new recipe of image-to-video diffusion paradigm that pivots on image noise prior derived from static image to jointly trigger inter-frame relational reasoning and ease the coherent temporal modeling via temporal residual learning. Technically, the image noise prior is first attained through one-step backward diffusion process based on both static image and noised video latent codes. Next, TRIP executes a residual-like dual-path scheme for noise prediction: 1) a shortcut path that directly takes image noise prior as the reference noise of each frame to amplify the alignment between the first frame and subsequent frames; 2) a residual path that employs 3D-UNet over noised video and static image latent codes to enable inter-frame relational reasoning, thereby easing the learning of the residual noise for each frame. Furthermore, both reference and residual noise of each frame are dynamically merged via attention mechanism for final video generation. Extensive experiments on WebVid-10M, DTDB and MSR-VTT datasets demonstrate the effectiveness of our TRIP for image-to-video generation. Please see our project page at https://trip-i2v.github.io/TRIP/.

Colorizing line art is a pivotal task in the production of hand-drawn cel animation. This typically involves digital painters using a paint bucket tool to manually color each segment enclosed by lines, based on RGB values predetermined by a color designer. This frame-by-frame process is both arduous and time-intensive. Current automated methods mainly focus on segment matching. This technique migrates colors from a reference to the target frame by aligning features within line-enclosed segments across frames. However, issues like occlusion and wrinkles in animations often disrupt these direct correspondences, leading to mismatches. In this work, we introduce a new learning-based inclusion matching pipeline, which directs the network to comprehend the inclusion relationships between segments rather than relying solely on direct visual correspondences. Our method features a two-stage pipeline that integrates a coarse color warping module with an inclusion matching module, enabling more nuanced and accurate colorization. To facilitate the training of our network, we also develope a unique dataset, referred to as PaintBucket-Character. This dataset includes rendered line arts alongside their colorized counterparts, featuring various 3D characters. Extensive experiments demonstrate the effectiveness and superiority of our method over existing techniques.

With the development of large language models, many remarkable linguistic systems like ChatGPT have thrived and achieved astonishing success on many tasks, showing the incredible power of foundation models. In the spirit of unleashing the capability of foundation models on vision tasks, the Segment Anything Model (SAM), a vision foundation model for image segmentation, has been proposed recently and presents strong zero-shot ability on many downstream 2D tasks. However, whether SAM can be adapted to 3D vision tasks has yet to be explored, especially 3D object detection. With this inspiration, we explore adapting the zero-shot ability of SAM to 3D object detection in this paper. We propose a SAM-powered BEV processing pipeline to detect objects and get promising results on the large-scale Waymo open dataset. As an early attempt, our method takes a step toward 3D object detection with vision foundation models and presents the opportunity to unleash their power on 3D vision tasks. The code is released at https://github.com/DYZhang09/SAM3D.

Recently, open-vocabulary learning has emerged to accomplish segmentation for arbitrary categories of text-based descriptions, which popularizes the segmentation system to more general-purpose application scenarios. However, existing methods devote to designing specialized architectures or parameters for specific segmentation tasks. These customized design paradigms lead to fragmentation between various segmentation tasks, thus hindering the uniformity of segmentation models. Hence in this paper, we propose FreeSeg, a generic framework to accomplish Unified, Universal and Open-Vocabulary Image Segmentation. FreeSeg optimizes an all-in-one network via one-shot training and employs the same architecture and parameters to handle diverse segmentation tasks seamlessly in the inference procedure. Additionally, adaptive prompt learning facilitates the unified model to capture task-aware and category-sensitive concepts, improving model robustness in multi-task and varied scenarios. Extensive experimental results demonstrate that FreeSeg establishes new state-of-the-art results in performance and generalization on three segmentation tasks, which outperforms the best task-specific architectures by a large margin: 5.5% mIoU on semantic segmentation, 17.6% mAP on instance segmentation, 20.1% PQ on panoptic segmentation for the unseen class on COCO.

Semantic segmentation of medical images aims to associate a pixel with a label in a medical image without human initialization. The success of semantic segmentation algorithms is contingent on the availability of high-quality imaging data with corresponding labels provided by experts. We sought to create a large collection of annotated medical image datasets of various clinically relevant anatomies available under open source license to facilitate the development of semantic segmentation algorithms. Such a resource would allow: 1) objective assessment of general-purpose segmentation methods through comprehensive benchmarking and 2) open and free access to medical image data for any researcher interested in the problem domain. Through a multi-institutional effort, we generated a large, curated dataset representative of several highly variable segmentation tasks that was used in a crowd-sourced challenge - the Medical Segmentation Decathlon held during the 2018 Medical Image Computing and Computer Aided Interventions Conference in Granada, Spain. Here, we describe these ten labeled image datasets so that these data may be effectively reused by the research community.

Precise image segmentation provides clinical study with meaningful and well-structured information. Despite the remarkable progress achieved in medical image segmentation, there is still an absence of foundation segmentation model that can segment a wide range of anatomical categories with easy user interaction. In this paper, we propose a universal and interactive volumetric medical image segmentation model, named SegVol. By training on 90k unlabeled Computed Tomography (CT) volumes and 6k labeled CTs, this foundation model supports the segmentation of over 200 anatomical categories using semantic and spatial prompts. Extensive experiments verify that SegVol outperforms the state of the art by a large margin on multiple segmentation benchmarks. Notably, on three challenging lesion datasets, our method achieves around 20% higher Dice score than nnU-Net. The model and data are publicly available at: https://github.com/BAAI-DCAI/SegVol.

The reference-based object segmentation tasks, namely referring image segmentation (RIS), few-shot image segmentation (FSS), referring video object segmentation (RVOS), and video object segmentation (VOS), aim to segment a specific object by utilizing either language or annotated masks as references. Despite significant progress in each respective field, current methods are task-specifically designed and developed in different directions, which hinders the activation of multi-task capabilities for these tasks. In this work, we end the current fragmented situation and propose UniRef++ to unify the four reference-based object segmentation tasks with a single architecture. At the heart of our approach is the proposed UniFusion module which performs multiway-fusion for handling different tasks with respect to their specified references. And a unified Transformer architecture is then adopted for achieving instance-level segmentation. With the unified designs, UniRef++ can be jointly trained on a broad range of benchmarks and can flexibly complete multiple tasks at run-time by specifying the corresponding references. We evaluate our unified models on various benchmarks. Extensive experimental results indicate that our proposed UniRef++ achieves state-of-the-art performance on RIS and RVOS, and performs competitively on FSS and VOS with a parameter-shared network. Moreover, we showcase that the proposed UniFusion module could be easily incorporated into the current advanced foundation model SAM and obtain satisfactory results with parameter-efficient finetuning. Codes and models are available at https://github.com/FoundationVision/UniRef.

Deep learning in the presence of noisy annotations has been studied extensively in classification, but much less in segmentation tasks. In this work, we study the learning dynamics of deep segmentation networks trained on inaccurately-annotated data. We discover a phenomenon that has been previously reported in the context of classification: the networks tend to first fit the clean pixel-level labels during an "early-learning" phase, before eventually memorizing the false annotations. However, in contrast to classification, memorization in segmentation does not arise simultaneously for all semantic categories. Inspired by these findings, we propose a new method for segmentation from noisy annotations with two key elements. First, we detect the beginning of the memorization phase separately for each category during training. This allows us to adaptively correct the noisy annotations in order to exploit early learning. Second, we incorporate a regularization term that enforces consistency across scales to boost robustness against annotation noise. Our method outperforms standard approaches on a medical-imaging segmentation task where noises are synthesized to mimic human annotation errors. It also provides robustness to realistic noisy annotations present in weakly-supervised semantic segmentation, achieving state-of-the-art results on PASCAL VOC 2012. Code is available at https://github.com/Kangningthu/ADELE

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as proliferation. This enables customized and more precise cancer treatments. However, accurate cell instance segmentation, necessary for further cell tracking and behavior analysis, is still challenging in scenarios with high cell concentration and overlapping edges. Within this framework, we propose a novel cell instance segmentation approach based on the well-known U-Net architecture. To enforce the learning of morphological information per pixel, a deep distance transformer (DDT) acts as a back-bone model. The DDT output is subsequently used to train a top-model. The following top-models are considered: a three-class (e.g., foreground, background and cell border) U-net, and a watershed transform. The obtained results suggest a performance boost over traditional U-Net architectures. This opens an interesting research line around the idea of injecting morphological information into a fully convolutional model.

Current approaches to dichotomous image segmentation (DIS) treat image matting and object segmentation as fundamentally different tasks. As improvements in image segmentation become increasingly challenging to achieve, combining image matting and grayscale segmentation techniques offers promising new directions for architectural innovation. Inspired by the possibility of aligning these two model tasks, we propose a new architectural approach for DIS called Confidence-Guided Matting (CGM). We created the first CGM model called Background Erase Network (BEN). BEN is comprised of two components: BEN Base for initial segmentation and BEN Refiner for confidence refinement. Our approach achieves substantial improvements over current state-of-the-art methods on the DIS5K validation dataset, demonstrating that matting-based refinement can significantly enhance segmentation quality. This work opens new possibilities for cross-pollination between matting and segmentation techniques in computer vision.

Recent text-to-image diffusion models are able to generate convincing results of unprecedented quality. However, it is nearly impossible to control the shapes of different regions/objects or their layout in a fine-grained fashion. Previous attempts to provide such controls were hindered by their reliance on a fixed set of labels. To this end, we present SpaText - a new method for text-to-image generation using open-vocabulary scene control. In addition to a global text prompt that describes the entire scene, the user provides a segmentation map where each region of interest is annotated by a free-form natural language description. Due to lack of large-scale datasets that have a detailed textual description for each region in the image, we choose to leverage the current large-scale text-to-image datasets and base our approach on a novel CLIP-based spatio-textual representation, and show its effectiveness on two state-of-the-art diffusion models: pixel-based and latent-based. In addition, we show how to extend the classifier-free guidance method in diffusion models to the multi-conditional case and present an alternative accelerated inference algorithm. Finally, we offer several automatic evaluation metrics and use them, in addition to FID scores and a user study, to evaluate our method and show that it achieves state-of-the-art results on image generation with free-form textual scene control.

Star-convex shapes arise across bio-microscopy and radiology in the form of nuclei, nodules, metastases, and other units. Existing instance segmentation networks for such structures train on densely labeled instances for each dataset, which requires substantial and often impractical manual annotation effort. Further, significant reengineering or finetuning is needed when presented with new datasets and imaging modalities due to changes in contrast, shape, orientation, resolution, and density. We present AnyStar, a domain-randomized generative model that simulates synthetic training data of blob-like objects with randomized appearance, environments, and imaging physics to train general-purpose star-convex instance segmentation networks. As a result, networks trained using our generative model do not require annotated images from unseen datasets. A single network trained on our synthesized data accurately 3D segments C. elegans and P. dumerilii nuclei in fluorescence microscopy, mouse cortical nuclei in micro-CT, zebrafish brain nuclei in EM, and placental cotyledons in human fetal MRI, all without any retraining, finetuning, transfer learning, or domain adaptation. Code is available at https://github.com/neel-dey/AnyStar.

Current knowledge distillation approaches in semantic segmentation tend to adopt a holistic approach that treats all spatial locations equally. However, for dense prediction, students' predictions on edge regions are highly uncertain due to contextual information leakage, requiring higher spatial sensitivity knowledge than the body regions. To address this challenge, this paper proposes a novel approach called boundary-privileged knowledge distillation (BPKD). BPKD distills the knowledge of the teacher model's body and edges separately to the compact student model. Specifically, we employ two distinct loss functions: (i) edge loss, which aims to distinguish between ambiguous classes at the pixel level in edge regions; (ii) body loss, which utilizes shape constraints and selectively attends to the inner-semantic regions. Our experiments demonstrate that the proposed BPKD method provides extensive refinements and aggregation for edge and body regions. Additionally, the method achieves state-of-the-art distillation performance for semantic segmentation on three popular benchmark datasets, highlighting its effectiveness and generalization ability. BPKD shows consistent improvements across a diverse array of lightweight segmentation structures, including both CNNs and transformers, underscoring its architecture-agnostic adaptability. The code is available at https://github.com/AkideLiu/BPKD.

We introduce a new paradigm for generative modeling built on Continuous Normalizing Flows (CNFs), allowing us to train CNFs at unprecedented scale. Specifically, we present the notion of Flow Matching (FM), a simulation-free approach for training CNFs based on regressing vector fields of fixed conditional probability paths. Flow Matching is compatible with a general family of Gaussian probability paths for transforming between noise and data samples -- which subsumes existing diffusion paths as specific instances. Interestingly, we find that employing FM with diffusion paths results in a more robust and stable alternative for training diffusion models. Furthermore, Flow Matching opens the door to training CNFs with other, non-diffusion probability paths. An instance of particular interest is using Optimal Transport (OT) displacement interpolation to define the conditional probability paths. These paths are more efficient than diffusion paths, provide faster training and sampling, and result in better generalization. Training CNFs using Flow Matching on ImageNet leads to consistently better performance than alternative diffusion-based methods in terms of both likelihood and sample quality, and allows fast and reliable sample generation using off-the-shelf numerical ODE solvers.

Image segmentation remains a pivotal component in medical image analysis, aiding in the extraction of critical information for precise diagnostic practices. With the advent of deep learning, automated image segmentation methods have risen to prominence, showcasing exceptional proficiency in processing medical imagery. Motivated by the Segment Anything Model (SAM)-a foundational model renowned for its remarkable precision and robust generalization capabilities in segmenting 2D natural images-we introduce SAM3D, an innovative adaptation tailored for 3D volumetric medical image analysis. Unlike current SAM-based methods that segment volumetric data by converting the volume into separate 2D slices for individual analysis, our SAM3D model processes the entire 3D volume image in a unified approach. Extensive experiments are conducted on multiple medical image datasets to demonstrate that our network attains competitive results compared with other state-of-the-art methods in 3D medical segmentation tasks while being significantly efficient in terms of parameters. Code and checkpoints are available at https://github.com/UARK-AICV/SAM3D.

In this work, we present SEEM, a promptable and interactive model for segmenting everything everywhere all at once in an image, as shown in Fig.1. In SEEM, we propose a novel decoding mechanism that enables diverse prompting for all types of segmentation tasks, aiming at a universal segmentation interface that behaves like large language models (LLMs). More specifically, SEEM is designed with four desiderata: i) Versatility. We introduce a new visual prompt to unify different spatial queries including points, boxes, scribbles and masks, which can further generalize to a different referring image; ii) Compositionality. We learn a joint visual-semantic space between text and visual prompts, which facilitates the dynamic composition of two prompt types required for various segmentation tasks; iii) Interactivity. We further incorporate learnable memory prompts into the decoder to retain segmentation history through mask-guided cross-attention from decoder to image features; and iv) Semantic-awareness. We use a text encoder to encode text queries and mask labels into the same semantic space for open-vocabulary segmentation. We conduct a comprehensive empirical study to validate the effectiveness of SEEM across diverse segmentation tasks. Notably, our single SEEM model achieves competitive performance across interactive segmentation, generic segmentation, referring segmentation, and video object segmentation on 9 datasets with minimum 1/100 supervision. Furthermore, SEEM showcases a remarkable capacity for generalization to novel prompts or their combinations, rendering it a readily universal image segmentation interface.

Accurate retinal vessel (RV) segmentation is a crucial step in the quantitative assessment of retinal vasculature, which is needed for the early detection of retinal diseases and other conditions. Numerous studies have been conducted to tackle the problem of segmenting vessels automatically using a pixel-wise classification approach. The common practice of creating ground truth labels is to categorize pixels as foreground and background. This approach is, however, biased, and it ignores the uncertainty of a human annotator when it comes to annotating e.g. thin vessels. In this work, we propose a simple and effective method that casts the RV segmentation task as an image-level regression. For this purpose, we first introduce a novel Segmentation Annotation Uncertainty-Aware (SAUNA) transform, which adds pixel uncertainty to the ground truth using the pixel's closeness to the annotation boundary and vessel thickness. To train our model with soft labels, we generalize the earlier proposed Jaccard metric loss to arbitrary hypercubes for soft Jaccard index (Intersection-over-Union) optimization. Additionally, we employ a stable version of the Focal-L1 loss for pixel-wise regression. We conduct thorough experiments and compare our method to a diverse set of baselines across 5 retinal image datasets. Our empirical results indicate that the integration of the SAUNA transform and these segmentation losses led to significant performance boosts for different segmentation models. Particularly, our methodology enables UNet-like architectures to substantially outperform computational-intensive baselines. Our implementation is available at https://github.com/Oulu-IMEDS/SAUNA.

Segmenting and recognizing diverse object parts is crucial in computer vision and robotics. Despite significant progress in object segmentation, part-level segmentation remains underexplored due to complex boundaries and scarce annotated data. To address this, we propose a novel Weakly-supervised Part Segmentation (WPS) setting and an approach called WPS-SAM, built on the large-scale pre-trained vision foundation model, Segment Anything Model (SAM). WPS-SAM is an end-to-end framework designed to extract prompt tokens directly from images and perform pixel-level segmentation of part regions. During its training phase, it only uses weakly supervised labels in the form of bounding boxes or points. Extensive experiments demonstrate that, through exploiting the rich knowledge embedded in pre-trained foundation models, WPS-SAM outperforms other segmentation models trained with pixel-level strong annotations. Specifically, WPS-SAM achieves 68.93% mIOU and 79.53% mACC on the PartImageNet dataset, surpassing state-of-the-art fully supervised methods by approximately 4% in terms of mIOU.

Clinicians are often very sceptical about applying automatic image processing approaches, especially deep learning based methods, in practice. One main reason for this is the black-box nature of these approaches and the inherent problem of missing insights of the automatically derived decisions. In order to increase trust in these methods, this paper presents approaches that help to interpret and explain the results of deep learning algorithms by depicting the anatomical areas which influence the decision of the algorithm most. Moreover, this research presents a unified framework, TorchEsegeta, for applying various interpretability and explainability techniques for deep learning models and generate visual interpretations and explanations for clinicians to corroborate their clinical findings. In addition, this will aid in gaining confidence in such methods. The framework builds on existing interpretability and explainability techniques that are currently focusing on classification models, extending them to segmentation tasks. In addition, these methods have been adapted to 3D models for volumetric analysis. The proposed framework provides methods to quantitatively compare visual explanations using infidelity and sensitivity metrics. This framework can be used by data scientists to perform post-hoc interpretations and explanations of their models, develop more explainable tools and present the findings to clinicians to increase their faith in such models. The proposed framework was evaluated based on a use case scenario of vessel segmentation models trained on Time-of-fight (TOF) Magnetic Resonance Angiogram (MRA) images of the human brain. Quantitative and qualitative results of a comparative study of different models and interpretability methods are presented. Furthermore, this paper provides an extensive overview of several existing interpretability and explainability methods.

Text- or image-to-3D generators and 3D scanners can now produce 3D assets with high-quality shapes and textures. These assets typically consist of a single, fused representation, like an implicit neural field, a Gaussian mixture, or a mesh, without any useful structure. However, most applications and creative workflows require assets to be made of several meaningful parts that can be manipulated independently. To address this gap, we introduce PartGen, a novel approach that generates 3D objects composed of meaningful parts starting from text, an image, or an unstructured 3D object. First, given multiple views of a 3D object, generated or rendered, a multi-view diffusion model extracts a set of plausible and view-consistent part segmentations, dividing the object into parts. Then, a second multi-view diffusion model takes each part separately, fills in the occlusions, and uses those completed views for 3D reconstruction by feeding them to a 3D reconstruction network. This completion process considers the context of the entire object to ensure that the parts integrate cohesively. The generative completion model can make up for the information missing due to occlusions; in extreme cases, it can hallucinate entirely invisible parts based on the input 3D asset. We evaluate our method on generated and real 3D assets and show that it outperforms segmentation and part-extraction baselines by a large margin. We also showcase downstream applications such as 3D part editing.

3D part segmentation is a crucial and challenging task in 3D perception, playing a vital role in applications such as robotics, 3D generation, and 3D editing. Recent methods harness the powerful Vision Language Models (VLMs) for 2D-to-3D knowledge distillation, achieving zero-shot 3D part segmentation. However, these methods are limited by their reliance on text prompts, which restricts the scalability to large-scale unlabeled datasets and the flexibility in handling part ambiguities. In this work, we introduce SAMPart3D, a scalable zero-shot 3D part segmentation framework that segments any 3D object into semantic parts at multiple granularities, without requiring predefined part label sets as text prompts. For scalability, we use text-agnostic vision foundation models to distill a 3D feature extraction backbone, allowing scaling to large unlabeled 3D datasets to learn rich 3D priors. For flexibility, we distill scale-conditioned part-aware 3D features for 3D part segmentation at multiple granularities. Once the segmented parts are obtained from the scale-conditioned part-aware 3D features, we use VLMs to assign semantic labels to each part based on the multi-view renderings. Compared to previous methods, our SAMPart3D can scale to the recent large-scale 3D object dataset Objaverse and handle complex, non-ordinary objects. Additionally, we contribute a new 3D part segmentation benchmark to address the lack of diversity and complexity of objects and parts in existing benchmarks. Experiments show that our SAMPart3D significantly outperforms existing zero-shot 3D part segmentation methods, and can facilitate various applications such as part-level editing and interactive segmentation.

Anatomical segmentation is a fundamental task in medical image computing, generally tackled with fully convolutional neural networks which produce dense segmentation masks. These models are often trained with loss functions such as cross-entropy or Dice, which assume pixels to be independent of each other, thus ignoring topological errors and anatomical inconsistencies. We address this limitation by moving from pixel-level to graph representations, which allow to naturally incorporate anatomical constraints by construction. To this end, we introduce HybridGNet, an encoder-decoder neural architecture that leverages standard convolutions for image feature encoding and graph convolutional neural networks (GCNNs) to decode plausible representations of anatomical structures. We also propose a novel image-to-graph skip connection layer which allows localized features to flow from standard convolutional blocks to GCNN blocks, and show that it improves segmentation accuracy. The proposed architecture is extensively evaluated in a variety of domain shift and image occlusion scenarios, and audited considering different types of demographic domain shift. Our comprehensive experimental setup compares HybridGNet with other landmark and pixel-based models for anatomical segmentation in chest x-ray images, and shows that it produces anatomically plausible results in challenging scenarios where other models tend to fail.

We present Set-of-Mark (SoM), a new visual prompting method, to unleash the visual grounding abilities of large multimodal models (LMMs), such as GPT-4V. As illustrated in Fig. 1 (right), we employ off-the-shelf interactive segmentation models, such as SAM, to partition an image into regions at different levels of granularity, and overlay these regions with a set of marks e.g., alphanumerics, masks, boxes. Using the marked image as input, GPT-4V can answer the questions that require visual grounding. We perform a comprehensive empirical study to validate the effectiveness of SoM on a wide range of fine-grained vision and multimodal tasks. For example, our experiments show that GPT-4V with SoM outperforms the state-of-the-art fully-finetuned referring segmentation model on RefCOCOg in a zero-shot setting.

Depth-aware panoptic segmentation is an emerging topic in computer vision which combines semantic and geometric understanding for more robust scene interpretation. Recent works pursue unified frameworks to tackle this challenge but mostly still treat it as two individual learning tasks, which limits their potential for exploring cross-domain information. We propose a deeply unified framework for depth-aware panoptic segmentation, which performs joint segmentation and depth estimation both in a per-segment manner with identical object queries. To narrow the gap between the two tasks, we further design a geometric query enhancement method, which is able to integrate scene geometry into object queries using latent representations. In addition, we propose a bi-directional guidance learning approach to facilitate cross-task feature learning by taking advantage of their mutual relations. Our method sets the new state of the art for depth-aware panoptic segmentation on both Cityscapes-DVPS and SemKITTI-DVPS datasets. Moreover, our guidance learning approach is shown to deliver performance improvement even under incomplete supervision labels.

Instance segmentation datasets play a crucial role in training accurate and robust computer vision models. However, obtaining accurate mask annotations to produce high-quality segmentation datasets is a costly and labor-intensive process. In this work, we show how this issue can be mitigated by starting with small annotated instance segmentation datasets and augmenting them to effectively obtain a sizeable annotated dataset. We achieve that by creating variations of the available annotated object instances in a way that preserves the provided mask annotations, thereby resulting in new image-mask pairs to be added to the set of annotated images. Specifically, we generate new images using a diffusion-based inpainting model to fill out the masked area with a desired object class by guiding the diffusion through the object outline. We show that the object outline provides a simple, but also reliable and convenient training-free guidance signal for the underlying inpainting model that is often sufficient to fill out the mask with an object of the correct class without further text guidance and preserve the correspondence between generated images and the mask annotations with high precision. Our experimental results reveal that our method successfully generates realistic variations of object instances, preserving their shape characteristics while introducing diversity within the augmented area. We also show that the proposed method can naturally be combined with text guidance and other image augmentation techniques.

Large, fine-grained image segmentation datasets, annotated at pixel-level, are difficult to obtain, particularly in medical imaging, where annotations also require expert knowledge. Weakly-supervised learning can train models by relying on weaker forms of annotation, such as scribbles. Here, we learn to segment using scribble annotations in an adversarial game. With unpaired segmentation masks, we train a multi-scale GAN to generate realistic segmentation masks at multiple resolutions, while we use scribbles to learn their correct position in the image. Central to the model's success is a novel attention gating mechanism, which we condition with adversarial signals to act as a shape prior, resulting in better object localization at multiple scales. Subject to adversarial conditioning, the segmentor learns attention maps that are semantic, suppress the noisy activations outside the objects, and reduce the vanishing gradient problem in the deeper layers of the segmentor. We evaluated our model on several medical (ACDC, LVSC, CHAOS) and non-medical (PPSS) datasets, and we report performance levels matching those achieved by models trained with fully annotated segmentation masks. We also demonstrate extensions in a variety of settings: semi-supervised learning; combining multiple scribble sources (a crowdsourcing scenario) and multi-task learning (combining scribble and mask supervision). We release expert-made scribble annotations for the ACDC dataset, and the code used for the experiments, at https://vios-s.github.io/multiscale-adversarial-attention-gates

An instance with a bad mask might make a composite image that uses it look fake. This encourages us to learn segmentation by generating realistic composite images. To achieve this, we propose a novel framework that exploits a new proposed prior called the independence prior based on Generative Adversarial Networks (GANs). The generator produces an image with multiple category-specific instance providers, a layout module and a composition module. Firstly, each provider independently outputs a category-specific instance image with a soft mask. Then the provided instances' poses are corrected by the layout module. Lastly, the composition module combines these instances into a final image. Training with adversarial loss and penalty for mask area, each provider learns a mask that is as small as possible but enough to cover a complete category-specific instance. Weakly supervised semantic segmentation methods widely use grouping cues modeling the association between image parts, which are either artificially designed or learned with costly segmentation labels or only modeled on local pairs. Unlike them, our method automatically models the dependence between any parts and learns instance segmentation. We apply our framework in two cases: (1) Foreground segmentation on category-specific images with box-level annotation. (2) Unsupervised learning of instance appearances and masks with only one image of homogeneous object cluster (HOC). We get appealing results in both tasks, which shows the independence prior is useful for instance segmentation and it is possible to unsupervisedly learn instance masks with only one image.

The success of Deep Neural Network (DNN) models significantly depends on the quality of provided annotations. In medical image segmentation, for example, having multiple expert annotations for each data point is common to minimize subjective annotation bias. Then, the goal of estimation is to filter out the label noise and recover the ground-truth masks, which are not explicitly given. This paper proposes a probabilistic model for noisy observations that allows us to build a confident classification and segmentation models. To accomplish it, we explicitly model label noise and introduce a new information-based regularization that pushes the network to recover the ground-truth labels. In addition, for segmentation task we adjust the loss function by prioritizing learning in high-confidence regions where all the annotators agree on labeling. We evaluate the proposed method on a series of classification tasks such as noisy versions of MNIST, CIFAR-10, Fashion-MNIST datasets as well as CIFAR-10N, which is real-world dataset with noisy human annotations. Additionally, for segmentation task, we consider several medical imaging datasets, such as, LIDC and RIGA that reflect real-world inter-variability among multiple annotators. Our experiments show that our algorithm outperforms state-of-the-art solutions for the considered classification and segmentation problems.

Deep learning models have shown their potential for several applications. However, most of the models are opaque and difficult to trust due to their complex reasoning - commonly known as the black-box problem. Some fields, such as medicine, require a high degree of transparency to accept and adopt such technologies. Consequently, creating explainable/interpretable models or applying post-hoc methods on classifiers to build trust in deep learning models are required. Moreover, deep learning methods can be used for segmentation tasks, which typically require hard-to-obtain, time-consuming manually-annotated segmentation labels for training. This paper introduces three inherently-explainable classifiers to tackle both of these problems as one. The localisation heatmaps provided by the networks -- representing the models' focus areas and being used in classification decision-making -- can be directly interpreted, without requiring any post-hoc methods to derive information for model explanation. The models are trained by using the input image and only the classification labels as ground-truth in a supervised fashion - without using any information about the location of the region of interest (i.e. the segmentation labels), making the segmentation training of the models weakly-supervised through classification labels. The final segmentation is obtained by thresholding these heatmaps. The models were employed for the task of multi-class brain tumour classification using two different datasets, resulting in the best F1-score of 0.93 for the supervised classification task while securing a median Dice score of 0.67pm0.08 for the weakly-supervised segmentation task. Furthermore, the obtained accuracy on a subset of tumour-only images outperformed the state-of-the-art glioma tumour grading binary classifiers with the best model achieving 98.7\% accuracy.

The Diffusion Model has not only garnered noteworthy achievements in the realm of image generation but has also demonstrated its potential as an effective pretraining method utilizing unlabeled data. Drawing from the extensive potential unveiled by the Diffusion Model in both semantic correspondence and open vocabulary segmentation, our work initiates an investigation into employing the Latent Diffusion Model for Few-shot Semantic Segmentation. Recently, inspired by the in-context learning ability of large language models, Few-shot Semantic Segmentation has evolved into In-context Segmentation tasks, morphing into a crucial element in assessing generalist segmentation models. In this context, we concentrate on Few-shot Semantic Segmentation, establishing a solid foundation for the future development of a Diffusion-based generalist model for segmentation. Our initial focus lies in understanding how to facilitate interaction between the query image and the support image, resulting in the proposal of a KV fusion method within the self-attention framework. Subsequently, we delve deeper into optimizing the infusion of information from the support mask and simultaneously re-evaluating how to provide reasonable supervision from the query mask. Based on our analysis, we establish a simple and effective framework named DiffewS, maximally retaining the original Latent Diffusion Model's generative framework and effectively utilizing the pre-training prior. Experimental results demonstrate that our method significantly outperforms the previous SOTA models in multiple settings.

Fully automatic cardiac segmentation can be a fast and reproducible method to extract clinical measurements from an echocardiography examination. The U-Net architecture is the current state-of-the-art deep learning architecture for medical segmentation and can segment cardiac structures in real-time with average errors comparable to inter-observer variability. However, this architecture still generates large outliers that are often anatomically incorrect. This work uses the concept of graph convolutional neural networks that predict the contour points of the structures of interest instead of labeling each pixel. We propose a graph architecture that uses two convolutional rings based on cardiac anatomy and show that this eliminates anatomical incorrect multi-structure segmentations on the publicly available CAMUS dataset. Additionally, this work contributes with an ablation study on the graph convolutional architecture and an evaluation of clinical measurements on the clinical HUNT4 dataset. Finally, we propose to use the inter-model agreement of the U-Net and the graph network as a predictor of both the input and segmentation quality. We show this predictor can detect out-of-distribution and unsuitable input images in real-time. Source code is available online: https://github.com/gillesvntnu/GCN_multistructure

Recently, the emergence of diffusion models has opened up new opportunities for single-view reconstruction. However, all the existing methods represent the target object as a closed mesh devoid of any structural information, thus neglecting the part-based structure, which is crucial for many downstream applications, of the reconstructed shape. Moreover, the generated meshes usually suffer from large noises, unsmooth surfaces, and blurry textures, making it challenging to obtain satisfactory part segments using 3D segmentation techniques. In this paper, we present Part123, a novel framework for part-aware 3D reconstruction from a single-view image. We first use diffusion models to generate multiview-consistent images from a given image, and then leverage Segment Anything Model (SAM), which demonstrates powerful generalization ability on arbitrary objects, to generate multiview segmentation masks. To effectively incorporate 2D part-based information into 3D reconstruction and handle inconsistency, we introduce contrastive learning into a neural rendering framework to learn a part-aware feature space based on the multiview segmentation masks. A clustering-based algorithm is also developed to automatically derive 3D part segmentation results from the reconstructed models. Experiments show that our method can generate 3D models with high-quality segmented parts on various objects. Compared to existing unstructured reconstruction methods, the part-aware 3D models from our method benefit some important applications, including feature-preserving reconstruction, primitive fitting, and 3D shape editing.

Despite significant progress in 3D point cloud segmentation, existing methods primarily address specific tasks and depend on explicit instructions to identify targets, lacking the capability to infer and understand implicit user intentions in a unified framework. In this work, we propose a model, called SegPoint, that leverages the reasoning capabilities of a multi-modal Large Language Model (LLM) to produce point-wise segmentation masks across a diverse range of tasks: 1) 3D instruction segmentation, 2) 3D referring segmentation, 3) 3D semantic segmentation, and 4) 3D open-vocabulary semantic segmentation. To advance 3D instruction research, we introduce a new benchmark, Instruct3D, designed to evaluate segmentation performance from complex and implicit instructional texts, featuring 2,565 point cloud-instruction pairs. Our experimental results demonstrate that SegPoint achieves competitive performance on established benchmarks such as ScanRefer for referring segmentation and ScanNet for semantic segmentation, while delivering outstanding outcomes on the Instruct3D dataset. To our knowledge, SegPoint is the first model to address these varied segmentation tasks within a single framework, achieving satisfactory performance.

We present SegGPT, a generalist model for segmenting everything in context. We unify various segmentation tasks into a generalist in-context learning framework that accommodates different kinds of segmentation data by transforming them into the same format of images. The training of SegGPT is formulated as an in-context coloring problem with random color mapping for each data sample. The objective is to accomplish diverse tasks according to the context, rather than relying on specific colors. After training, SegGPT can perform arbitrary segmentation tasks in images or videos via in-context inference, such as object instance, stuff, part, contour, and text. SegGPT is evaluated on a broad range of tasks, including few-shot semantic segmentation, video object segmentation, semantic segmentation, and panoptic segmentation. Our results show strong capabilities in segmenting in-domain and out-of-domain targets, either qualitatively or quantitatively.

Automatic diabetic retinopathy (DR) lesions segmentation makes great sense of assisting ophthalmologists in diagnosis. Although many researches have been conducted on this task, most prior works paid too much attention to the designs of networks instead of considering the pathological association for lesions. Through investigating the pathogenic causes of DR lesions in advance, we found that certain lesions are closed to specific vessels and present relative patterns to each other. Motivated by the observation, we propose a relation transformer block (RTB) to incorporate attention mechanisms at two main levels: a self-attention transformer exploits global dependencies among lesion features, while a cross-attention transformer allows interactions between lesion and vessel features by integrating valuable vascular information to alleviate ambiguity in lesion detection caused by complex fundus structures. In addition, to capture the small lesion patterns first, we propose a global transformer block (GTB) which preserves detailed information in deep network. By integrating the above blocks of dual-branches, our network segments the four kinds of lesions simultaneously. Comprehensive experiments on IDRiD and DDR datasets well demonstrate the superiority of our approach, which achieves competitive performance compared to state-of-the-arts.

Interactive 3D segmentation in radiance fields is an appealing task since its importance in 3D scene understanding and manipulation. However, existing methods face challenges in either achieving fine-grained, multi-granularity segmentation or contending with substantial computational overhead, inhibiting real-time interaction. In this paper, we introduce Segment Any 3D GAussians (SAGA), a novel 3D interactive segmentation approach that seamlessly blends a 2D segmentation foundation model with 3D Gaussian Splatting (3DGS), a recent breakthrough of radiance fields. SAGA efficiently embeds multi-granularity 2D segmentation results generated by the segmentation foundation model into 3D Gaussian point features through well-designed contrastive training. Evaluation on existing benchmarks demonstrates that SAGA can achieve competitive performance with state-of-the-art methods. Moreover, SAGA achieves multi-granularity segmentation and accommodates various prompts, including points, scribbles, and 2D masks. Notably, SAGA can finish the 3D segmentation within milliseconds, achieving nearly 1000x acceleration compared to previous SOTA. The project page is at https://jumpat.github.io/SAGA.

In this work, we address various segmentation tasks, each traditionally tackled by distinct or partially unified models. We propose OMG-Seg, One Model that is Good enough to efficiently and effectively handle all the segmentation tasks, including image semantic, instance, and panoptic segmentation, as well as their video counterparts, open vocabulary settings, prompt-driven, interactive segmentation like SAM, and video object segmentation. To our knowledge, this is the first model to handle all these tasks in one model and achieve satisfactory performance. We show that OMG-Seg, a transformer-based encoder-decoder architecture with task-specific queries and outputs, can support over ten distinct segmentation tasks and yet significantly reduce computational and parameter overhead across various tasks and datasets. We rigorously evaluate the inter-task influences and correlations during co-training. Code and models are available at https://github.com/lxtGH/OMG-Seg.

Longitudinal analysis has great potential to reveal developmental trajectories and monitor disease progression in medical imaging. This process relies on consistent and robust joint 4D segmentation. Traditional techniques are dependent on the similarity of images over time and the use of subject-specific priors to reduce random variation and improve the robustness and sensitivity of the overall longitudinal analysis. This is however slow and computationally intensive as subject-specific templates need to be rebuilt every time. The focus of this work to accelerate this analysis with the use of deep learning. The proposed approach is based on deep CNNs and incorporates semantic segmentation and provides a longitudinal relationship for the same subject. The proposed approach is based on deep CNNs and incorporates semantic segmentation and provides a longitudinal relationship for the same subject. The state of art using 3D patches as inputs to modified Unet provides results around {0.91 pm 0.5} Dice and using multi-view atlas in CNNs provide around the same results. In this work, different models are explored, each offers better accuracy and fast results while increasing the segmentation quality. These methods are evaluated on 135 scans from the EADC-ADNI Harmonized Hippocampus Protocol. Proposed CNN based segmentation approaches demonstrate how 2D segmentation using prior slices can provide similar results to 3D segmentation while maintaining good continuity in the 3D dimension and improved speed. Just using 2D modified sagittal slices provide us a better Dice and longitudinal analysis for a given subject. For the ADNI dataset, using the simple UNet CNN technique gives us {0.84 pm 0.5} and while using modified CNN techniques on the same input yields {0.89 pm 0.5}. Rate of atrophy and RMS error are calculated for several test cases using various methods and analyzed.

Semantic segmentation is a computer vision task that associates a label with each pixel in an image. Modern approaches tend to introduce class embeddings into semantic segmentation for deeply utilizing category semantics, and regard supervised class masks as final predictions. In this paper, we explore the mechanism of class embeddings and have an insight that more explicit and meaningful class embeddings can be generated based on class masks purposely. Following this observation, we propose ECENet, a new segmentation paradigm, in which class embeddings are obtained and enhanced explicitly during interacting with multi-stage image features. Based on this, we revisit the traditional decoding process and explore inverted information flow between segmentation masks and class embeddings. Furthermore, to ensure the discriminability and informativity of features from backbone, we propose a Feature Reconstruction module, which combines intrinsic and diverse branches together to ensure the concurrence of diversity and redundancy in features. Experiments show that our ECENet outperforms its counterparts on the ADE20K dataset with much less computational cost and achieves new state-of-the-art results on PASCAL-Context dataset. The code will be released at https://gitee.com/mindspore/models and https://github.com/Carol-lyh/ECENet.